For the development of novel antitumor agents, we designed and synthesized terpyridines, and their biological activities were evaluated. Although most of the newly prepared terpyridines showed strong cytotoxicity against several human cancer cell lines, [2,2';6',2"]-terpyridine displayed the most significant cytotoxicity.
Alkenes Q 0083A Facile Synthesis of α,α'-Bis(substituted-benzylidene)cycloalkanones and Substituted-Benzylidene Heteroaromatics: Utility of NaOAc as a Catalyst for Aldol-Type Reaction. -This protocol is characterized by good to high yields, simplicity of operation and the lack of by-products. -(RAHMAN, A. F. M. M.; JEONG, B.-S.; KIM, D. H.; PARK, J. K.; LEE, E. S.; JAHNG*, Y.; Tetrahedron 63 (2007) 11, 2426-2431; Coll. Pharm., Yeungnam Univ., Kyongsan 712-749, S. Korea; Eng.) -Nuesgen 25-057
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