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ObjectiveTo evaluate the reproducibility of the 75 g oral glucose tolerance test and factors associated with non-reproducible results in Cameroonian pregnant women.ResultsTwenty-seven of the 84 participants (32.1%) who did the first oral glucose tolerance test were diagnosed with gestational diabetes mellitus. There was no difference between the means of the glycaemic responses at T0 (p = 0.64), T30 (p = 0.08), T60 (p = 0.86), T90 (p = 0.51), and T120 (p = 0.34) between the two oral glucose tolerance test. Age (p = 0.001) and BMI (p = 0.001) were significantly associated with non-reproducible results. The reproducibility of the oral glucose tolerance test in this study was 74.2%, and the kappa statistic’s 0.46. In conclusion, the results of the oral glucose tolerance test were reproducible in only 74.2% of pregnant women in this study. This highlights that a single oral glucose tolerance test for the diagnosis of gestational diabetes mellitus should be interpreted with caution.Electronic supplementary materialThe online version of this article (10.1186/s13104-017-2944-7) contains supplementary material, which is available to authorized users.

Introduction: Our aim was to identify the risk factors of clinical birth asphyxia and subsequent newborn death in the presence of nuchal cord in a sub-Saharan Africa setting. Methodology: It was a six-months' case-control study involving 117 parturients whose babies presented with a nuchal cord at delivery. The study was carried out at the Yaoundé Gyneco-Obstetric and Pediatric Hospital, Cameroon, from January 1 st to June 30 th 2013. Results: The risk factors of clinical birth asphyxia identified were: first delivery, absence of obstetrical ultrasound during pregnancy, nuchal cord with more than one loop, duration of second stage of labor more than 30 minutes during vaginal delivery. The risk factors for newborn death from clinical birth asphyxia in the presence of nuchal cord were: maternal age < 20 years, first delivery, absence of obstetrical ultrasound during pregnancy, nuchal cord with more than one loop, tight nuchal cord, duration of second stage of labor more than 30 minutes during vaginal delivery. Conclusion: We recommend a systematic obstetrical ultrasound before labor, so as to detect the presence of a nuchal cord, its tightness and the number of loops. Also, cesarean section should be considered when a nuchal cord is associated with first delivery, tightness or multiple looping.

Sexual activity during pregnancy improves the prognosis of labor in Cameroonian women. In the absence of contraindications, consented unprotected heterosexual intercourse should be promoted in pregnant women.

BackgroundAlthough the adherence to stroke guidelines in high-income countries has been shown to be associated with improved patient outcomes, the research, development and implementation of rehabilitation related guidelines in African countries is lacking.ObjectivesThe purpose of this article is to describe how a group of front-line practitioners collaborated with academics and students to develop best practice guidelines (BPG) for the management and rehabilitation of stroke in adult patients in Cameroon.MethodA working group was established and adapted internationally recognised processes for the development of best practice guidelines. The group determined the scope of the guidelines, documented current practices, and critically appraised evidence to develop guidelines relevant to the Cameroon context.ResultsThe primary result of this project is best practice guidelines which provided an overview of the provision of stroke rehabilitation services in the region, and made 83 practice recommendations to improve these services. We also report on the successes and challenges encountered during the process, and the working group’s recommendations aimed at encouraging others to consider similar projects.ConclusionThis project demonstrated that there is interest and capacity for improving stroke rehabilitation practices and for stroke guideline development in Africa.

The Policy Research Working Paper Series disseminates the findings of work in progress to encourage the exchange of ideas about development issues. An objective of the series is to get the findings out quickly, even if the presentations are less than fully polished. The papers carry the names of the authors and should be cited accordingly. The findings, interpretations, and conclusions expressed in this paper are entirely those of the authors. They do not necessarily represent the views of the International Bank for Reconstruction and Development/World Bank and its affiliated organizations, or those of the Executive Directors of the World Bank or the governments they represent.

Objective: To identify the risk factors of intrapartal fetal death in a tertiary hospital in Yaoundé. Methods: It was a case-control study comparing 53 women who delivered with intrapartal fetal death to 106 women who delivered without intrapartal fetal death, carried out at the Yaoundé Gyneco-Obstetric and Pediatric Hospital, Cameroon. Results: The risk factors of intrapartal fetal death identified at bivariate analysis were: maternal age <20 years (OR = 3.1; CI = 1.1 -8.3), absence of regular income (OR = 2.4; CI = 1.2 -4.7), single motherhood (OR = 2.9; CI = 1.5 -5.7), illiteracy and primary level of education (OR = 4.7; CI = 1.9 -11.5), referral (OR = 5.0; CI = 2.5 -9.9), parity 0 and 1 (OR = 2.3; CI = 1.1 -4.5), no antenatal care (OR = 9.2; CI = 2.4 -35.6), number of antenatal visits <4 (OR = 4.2; CI = 2.1 -8.6), antenatal care in a health center (OR = 3.8; CI = 1.9 -7.5), antenatal care by a midwife (OR = 2.5; CI = 1.3 -4.9) or a nurse (OR = 5.2; CI = 1.4 -18.7), absence of malaria prophylaxis (OR = 10.6; CI = 2.9 -39.5), absence of obstetrical ultrasound (OR = 4.7; CI = 1.9 -10.9), prematurity (OR = 3.4; CI = 1.5 -7.3), abnormal presentation (OR = 2.6; CI = 1.1 -5.9), ruptured membranes at admission (OR = 2.7; CI = 1.3 -5.4), ruptured membranes >12 hours at admission (OR = 5.1; CI = 2.5 -10.3), stained amniotic fluid (OR = 4.8; CI = 2.4 -9.7), labor lasting more than 12 hours (OR = 18.1; CI = 8.0 -41.0), presence of maternal complications (OR = 4.7; CI = 2.2 -10.3), and presence of fetal complications (OR = 48.6; CI = 18.3 -129), particularly acute fetal distress (OR = 52.3; CI = (14.6 -186), cord prolapse (OR = 12.1; CI = 3.3 -43.4), and birth weight <2500 g (OR = 2.8; CI = 1.2 -6.6). Conclusion: Close attention should be offered to pregnant women, so as to identify these risk factors and promptly provide an appropriate management.

The objective of this study was to assess the effects of excessive weight gain during pregnancy on the outcome of cesarean delivery. It was a cohort study comparing the outcome of cesarean delivery between 56 pregnant women with excessive weight gain during pregnancy and 75 pregnant women with no excessive weight gain during pregnancy, consecutively recruited at the Yaoundé Gyneco-Obstetric and Pediatric Hospital, Cameroon. In women delivered by cesarean section, excessive weight gain during pregnancy was found to predispose to: time interval from parietal incision to fetal extraction of more than five minutes, duration of cesarean section more than 60 minutes, blood loss more than 1000 ml during surgery, postoperative maternal complications, especially sepsis, fetal weight >3.5 kg and macrosomia. A systematic screening of excessive weight gain should be offered to all pregnant women, so as to prevent the adverse effects of excessive gestational weight gain on cesarean outcome.