Assessment of adherence to iron supplementation among pregnant women in the Yaounde gynaeco-obstetric and paediatric hospital

Fouelifack, Florent Ymélé; Sama, Julius Dohbit; Sone, Charles Enome

doi:10.11604/pamj.2019.34.211.16446

Cited by 28 publications

(16 citation statements)

References 11 publications

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“…It shows the low perceived risk in the target group. The same observation was made in another study from Africa that primigravida listens and complies with medical advice, but as the age and burden of routine chores increases, the negligence of a woman towards her own health also increases [10].…”

Section: Discussionsupporting

confidence: 64%

A Cross-Sectional Study of Barriers in Prevention of Anemia in Pregnancy

Mishra¹,

Marwah²,

Divedi³

et al. 2021

Cureus

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Introduction Anemia in pregnancy is a significant health challenge in India and other developing countries. Various health programs aiming anemia prevention are existing in India for many decades. Despite that, anemia affects more than half of pregnant women. Our objective for performing this study was to evaluate the barriers in the prevention of anemia and to evaluate the perceptions and practices of anemic women towards their condition. Methods A cross-sectional questionnaire-based study, including 210 anemic women, was conducted in a tertiary care center in Delhi, India. In-depth interviews were conducted with 50 participants. Results Our important observations were that anemia was more prevalent in multigravida, and 43.80% of anemic patients were not taking iron supplements at the time of diagnosis. Chronic diseases were associated with 28.2% (n=59) of anemic women. Only 19% (n=40) of women sought antenatal care in the first and second trimester; the rest all booked themselves in the third trimester only. Twenty-two percent (n=48) of women reached our hospital after 36 weeks. Ignorance to anemia symptoms and the importance of consistent intake of the oral iron supplements was seen in 35.2% (n=74). One hundred and sixty-five (74.8%) women accepted that healthcare provider had informed them about iron-rich and high protein diet, but only 47.1% (n=98) actually made dietary modifications. Only 9.5% (n=20) of women were consistent in iron intake. Side effects of iron were reported by 30% (n=64) of women, and 15% (n=32) were intolerant to oral iron. Non-availability, change of residence, and forgetfulness were the main reasons behind non-compliance to oral iron. Conclusion We emphasize motivation for early registration, regular antenatal care, adequate iron supplement supply, and persistent counseling to ensure compliance to iron supplements by the antenatal care provider. Behavior-changing communication is needed at a societal level for antenatal mothers and their families aiming to prevent anemia in pregnancy instead of focussing on treatment.

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Section: Discussionsupporting

confidence: 64%

A Cross-Sectional Study of Barriers in Prevention of Anemia in Pregnancy

Mishra¹,

Marwah²,

Divedi³

et al. 2021

Cureus

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“…Most authors have reported this as one of the first three reasons for non-adherence in their study, with even higher values than we report. [14,20,25] Measures to assist women to remember taking these pills need to be reinforced. These include health talks at antenatal visits and on social media platforms, family support/reminders, directly observed therapy, pill diary, joining pregnancy clubs, amongst others.…”

Section: Discussionmentioning

confidence: 99%

The Impact of Iron and Folate Adherence on the Prevalence of Anaemia in Pregnant Nigerian Women

Ifeoluwapo¹,

Noel²,

Uchechukwu³

et al. 2020

JGO

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Introduction: The impact of adherence to taking prescribed medications for chronic illnesses has been widely studied with a view to understanding its role on disease burden. This has been extrapolated to the physiologic pregnancy state, where women are expected to take haematinics due to their susceptibility to anaemia. The prevalence of anaemia in pregnancy is reportedly high with more burden on developing countries. This has led to the recommendation of iron and folate supplements for women during pregnancy. Methods: We set out to determine the level of adherence (and deterrents) to taking iron and folate supplements as well as the prevalence of anaemia in pregnant women (18-45 years old) attending antenatal care at the Stella Obasanjo Women and Children Hospital (SOWCH) and the Central Hospital in Benin City, Nigeria between July-December, 2019. An association between occurrence of anaemia and adherence level was also assessed. Results: 400 pregnant women participated in this study. The mean age (±SD) of the study population was 30±4 years, mean gestational age (±SD) was 31±5 weeks. Majority of the women (82.0%) were in their third trimester, 17.5% and 0.5% in second and first trimesters respectively. Total adherence scores obtained ranged from 0-8, with 63.5% being non-adherent to taking their iron and folate supplements. Factors that influenced adherence positively were higher income (p=0.00) and being employed (p=0.01). Top three identified reason for non-adherence were forgetfulness to take prescribed supplement (62.5%), feeling too bored to take supplements daily (44.3%) and unavailability of supplements (38.0%). The mean Hb (±SD) was 10.9±1.1g/dl. The prevalence of anaemia in pregnancy was 46.8%, with mild (43.8%) and moderate (3.3%) forms only. Of the non-adherent group, 69.7% were anaemic versus 30.3% of the adherent group. There was an association between the occurence of anaemia and nonadherence to taking supplements (p=0.01). Conclusion: There is a high level of non-adherence to taking iron and folate, prevalence of anaemia, and an association between them. Benefits of adherence to these supplements should be reinforced to women of child bearing age.

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“…Vitamin D de ciency has been documented in up to 80% of the Indian population of all ages (10). Poor adherence to dosage regimes due to forgetfulness of the mothers, fear of side effects like gastritis, especially for iron supplements, poor coverage, and lack of knowledge are known challenges in the implementation of supplementation programs (11)(12)(13). A small amount of orally administered iron is absorbed, and the unabsorbed iron is associated with adverse effects such as gastritis and increased risk of gastrointestinal infections (14,15).…”

Section: Read Full License Introductionmentioning

confidence: 99%

Title: Efficacy of transdermal delivery of liposomal micronutrients through body oil massage on neurodevelopmental and micronutrient deficiency status in infants: Results of a randomized placebo controlled clinical trial

Apte¹,

Kapoor

Naik³

et al. 2021

Preprint

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Background: Micronutrient deficiency is a known cause of adverse neurodevelopment and growth. Poor adherence to oral regimes of micronutrient supplements is a known challenge during the implementation of supplementation programs. The present study evaluates the benefits of liposomal encapsulated micronutrient fortified body oils (LMF oil) that can be used for infant body massage in terms of neurodevelopment and prevention of deficiency. Study design: Double-blind randomized clinical trial Methods: 444 healthy infants aged 4-7weeks were randomized to receive either LMF oil (containing iron, vitamin D, folate, and vitamin B12) or placebo oil for gentle body massage till 12months of age. Blood samples were collected at 6 and 12 months for transferrin saturation (TSAT), hemoglobin, and 25-hydroxy vitamin (25-OH-D) levels. Mental and motor development was assessed at 12 months using developmental assessment for Indian Infants (DASII). Results: A total of 391 infants completed the study. There was no significant improvement in the hemoglobin in the intervention group at 12 months of age as compared to the placebo group [-0.50 vs.-0.54 gm%]. There was a marginally significant improvement in 25-OH-D at 12 months in the LMF oil group [+1.46vs.-0.18ng/ml, p=0.049]. In the subgroup of infants with moderate anemia, the intervention prevented the decline in hemoglobin at 12 months of age [adjusted mean change +0.11vs.-0.51gm%, p=0.043]. The mental or motor developmental quotients in the intervention group were not significantly different from those in the placebo group. Conclusion: Use of LMF oil for prevention of nutritional deficiency did not offer significant protection against nutritional anemia but prevented vitamin D deficiency to some extent with improvement in 25-OH-D at 12 months. In the subgroup of infants with moderate anemia, the intervention prevented the decline in hemoglobin at 12 months of age. The intervention did not result in significant improvement in mental or motor development. Further evaluation with increased doses needs to be undertaken.Trial registration: CTRI no: CTRI/2017/11/010710; dated 30/11/2017 [http://ctri.nic.in/Clinicaltrials/advancesearchmain.php ]

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Assessment of adherence to iron supplementation among pregnant women in the Yaounde gynaeco-obstetric and paediatric hospital

Cited by 28 publications

References 11 publications

A Cross-Sectional Study of Barriers in Prevention of Anemia in Pregnancy

A Cross-Sectional Study of Barriers in Prevention of Anemia in Pregnancy

The Impact of Iron and Folate Adherence on the Prevalence of Anaemia in Pregnant Nigerian Women

Title: Efficacy of transdermal delivery of liposomal micronutrients through body oil massage on neurodevelopmental and micronutrient deficiency status in infants: Results of a randomized placebo controlled clinical trial

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