Background:Vitamin D* called the sunshine vitamin is essential throughout life. Pregnancy is an altered physiological state in women, which requires proper nourishment. During gestation, this vitamin also plays an important role in development of the fetus. Objective:To observe the serum vitamin D (25diohydroxycholicalciferol) levels and serum calcium levels in the maternal blood during the three trimesters. Design: Observational Cross sectional study. Study population: Rural Mothers from Kancheepuram District, Tamil Nadu South India. We used 50 antenatal blood samples as experimental group and 15 as control group. The age group included 20-40 years. Blood samples were collected from 50 antenatal mothers between 20 – 40 years age group, from Obstetrics and Gynecology OPD for their routine antenatal check-ups, after getting duly signed informed consent. Control group had 15 women in the same age group not pregnant. Results: The results were tabulated. The mean value of 25dihydroxy vitamin D was observed very low than normal levels in all the three trimesters. The mean value of serum vitamin D in first trimester was 50.87 ng/ml, mean value of serum vitamin D in second trimester was 54.05.ng/ml, and mean third trimester vitamin D was 61.24ng/ml which was well below the optimum level of 100ng/ml. Conclusion: The vitamin D deficiency with normal level maintenance of serum calcium shows the compensatory mechanism that involves the normal calcium level maintence with resorption of bones by the osteoclastic actions to correct the deficit. If the deficiency is left untreated it may lead to faster osteoporosis in the mother.
*25 dihydroxycholicalciferol
Aneurysm is the swelling like enlargement present in the walls of the blood vessels. Saccular aneurysm is a rare entity when compared to fusiform aneurysm. Saccular aneurysm in the aortic arch is another rare location. We present a cadaveric case of a 55-year-old male cadaver in which saccular aneurysm was observed during routine dissection teaching for undergraduate students. The lesion was resected and sent for microscopic analysis. The lesion involved the vessel wall only. There were blood clots evident. This report presents the cadaveric presentation and histolopathological findings of the lesion.
Key words: Aneurysm, saccular aneurysm, aortic arch
Kenacort is a well-known synthetic glucocorticoid used in today's medical practice for various therapeutic uses. The drug has been known to induce cleft palate in rodents in specific doses. This study uses triamcinolone acetonide (TAC) as a teratogen for inducing cleft palate in rat embryos. The study discusses the molecular level action of TAC on the palatal mucosa in the rat palate. This study substantiates that the TAC given during the first trimester between 29th and 38th day of gestation can induce many congenital anomalies. The study shows an animal model to depict the drug toxicity on the pregnant Wistar albino rats.
Diabetes is a common non-transmittable disease in the world today. It is the fourth leading cause of mortality in most developed nations and there is significant proof that it is widespread in many developing and newly developed nations. Diabetes patients are at risk of developing is chemic heart disease, cerebrovascular disease and peripheral vascular disease, all of which can result in severe morbidity and death. The most widely used alternative therapy for glycaemic control is herbal medication. The effectiveness of botanicals in lowering sugar levels has been confirmed scientifically for a variety of Indian plant species. Numerous plants have been shown to be effective in treating a variety of systemic illnesses in traditional medical systems. Although many traditional/indigenous medical systems are more effective than modern medications, one of the biggest problems facing traditional medicine is the absence of comprehensive standardisation. The antioxidant, anti-inflammatory and hepatoprotective qualities of Katakakhadiradi kashayam may be responsible for its antidiabetic effects, but further research is needed to fully comprehend this kashayam's protective effects against a variety of ailments.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.