Neonatal lupus erythematosus (NLE) is an autoimmune disease characterized by a periorbital erythematous rash.Although post-inflammatory hypopigmentation and telangiectasias are known possible sequelae, these features may be particularly noticeable in skin of color. Herein, we describe two infants with skin of color in whom periorbital hypopigmentation and telangiectasias were clues to the diagnosis of NLE.
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