Despite promising therapeutic advances in the treatment of patients suffering from ovarian cancer, the prognosis remains poor. A sufficient supply of oxygen and nutrients is crucial for ovarian cancer, which is mainly provided by angiogenesis. The clinical use of new substances which trap proangiogenic substances or inhibit their intracellular transmembrane tyrosine kinase activity will increase as these substances have been shown to exhibit promising anti-tumorous activity. However, these new therapeutic approaches may lead to an increase in side effects such as diarrhea, hypertension, proteinuria, intestinal perforation and others, which are still relatively unknown, and these side effects will require adequate consecutive treatment.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.