A babesiose canina é uma hemoparasitose causada por agentes etiológicos do gênero Babesia. A utilização do diagnóstico clínico é imprecisa devido a existência de sinais clínicos inespecíficos, e os exames usados rotineiramente como o esfregaço sanguíneo apresenta muitos resultados falso negativos. Objetivo comparação da eficiência do diagnóstico por padrõeshematológicos, esfregaço sanguíneo, e por reação em cadeia da polimerase (PCR). Método trata-se de uma pesquisa realizada com de 80 cães que se encontravam sobre responsabilidade do Centro de Controle Zoonoses. Por meio da coleta de 3 ml de sangue venoso, por animal para a realização dos testes. Resultados, observou-se leve a moderada anemia nas 80 amostras analisadas, porém sem diferenças significativas nos parâmetros do hemograma dos cães positivos e negativos para a babesiose. Embora o diagnóstico pelo esfregaço sanguíneo tenha sido negativo, a PCR apresentou positividade de 46,2% (37/80) para Babesia canis. Foi identificado alto índice de resultados positivos para Babesia canis nos cães parasitados pelo carrapato vetor. Considerações finais a partir dos resultados encontrados, conclui-se que existe fragilidade nos exames utilizados rotineiramente para o diagnóstico da babesiose canina quando comparado ao diagnóstico molecular. Evidenciando anecessidade de implantação de novas metodologias para diagnóstico mais eficiente.
Bioinformática como ferramenta na análise de epitopos antigênicos no design de vacinas contra Anaplasma marginale, Leishmania spp., SARS-Cov-2 e toxina de Clostridium septicum Bioinformatics as a tool in the analysis of antigenic epitopes in the design of vaccines against Anaplasma marginale, Leishmania spp., SARS-Cov-2, and Clostridium septicum toxin
The eggs production through the confinement of chickens generates some inconveniences, among which the accumulation of manure, rich in organic matter that provides an environment conducive to the development and proliferation of Musca domestica. The objective of this work was to evaluate in a controlled environment the larvicidal efficacy in suppressing Musca domestica larvae. Material and methods used were the distribution of plastic trays exposed to oviposition in the farm sheds’ vicinity, applying the treatments in a controlled environment. Results shown that the isolated and intercropped treatments were effective in controlling the larvae. Concluding that the evaluation of the larvicidal efficacy of the Ciromanzine 50% principles; Triflumuron 48%; Ciromanzine 10%; and dolomitic limestone were effective in controlling larvae development in a controlled environment.
Introduction: American Tegumentary Leishmaniasis (ATL), or kala azar, is a serious chronic disease caused by Leishmania spp. It is an infectious and non-contagious disease that affects both humans and several species of wild and domestic animals, presenting the clinical forms of cutaneous, mucocutaneous and diffuse cutaneous. ATL is classified as a generalized zoonotic disease that has a global impact. It is caused by protozoa of the genus Leishmania and is considered a serious public health problem. Objective: To describe the epidemiological profile of cases found in Montes Claros-MG. Methodology: An epidemiological assessment was performed based on secondary data from SINAN/MS from January 2010 to December 2015. Results: From 2010 to 2015, 286 cases of ATL were registered, with the majority of cases occurring in children under 19 years of age (31.81%) and patients over 59 years (17.83%) had a lower percentage of disease involvement. The first choice drug used by patients was Glucantime (87.06%). The most affected gender was male (52.44%) and most patients had no comorbidities (76.96%). Conclusion: In Montes Claros, Minas Gerais, ATL presented high cases during the research period. In this sense, this study guides the development of new researches that address and monitor the spread of the disease by monitoring urban areas concomitantly with the capture of animals for the presence of the parasite, thus assisting in public health decision-making in controlling the disease.
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