MicroRNAs (miRNAs) represent a class of endogenous small non-coding RNAs with 18-25 nucleotides that are involved in diverse biological processes such as organogenesis (Lu et al., 2005), haematopoiesis, behaviour and innate/adaptive immunity (Leaman et al., 2005), cellular proliferation and differentiation (Hwang & Mendell, 2007), gene transcription and post-transcriptional processing (Diederichs & Haber, 2007), individual growth and development (Liu et al., 2009), embryo formation (Kocamis et al., 2013), epigenetics and immune regulation (Rusek et al., 2015).Similar to other types of molecules that regulate gene expression, many miRNAs vary significantly in different tissues and developmental stages, with highly conserved, temporal and tissue-spe-
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