The aim of this study was to examine the effect of several demographic variables on organizational culture, organizational citizenship behavior and job satisfaction. This comparative study extracted two samples from Egypt (127 participants) and Mexico (116 participants). Participants answered a 7-point Likert scale questionnaire and SPSS software was used to analyze the data. Results showed no demographic effect on the three constructs. From Egypt, differences were only observed on the managerial level regarding the market organizational culture. Results also showed significant results from Mexico on the managerial level and job satisfaction, organizational citizenship behavior, and clan and adhocracy organizational cultures. Further implications and future research directions are provided.