RESUMO:Neste ensaio foram monitoradas as concentrações do fibrinogênio plasmático e da fosfatase alcalina sérica e do fibrinogênio e fosfatase alcalina no fluido peritoneal (FP), nos períodos pré e pós operatórios, de equinos submetidos a enterorrafias invaginante (Grupo I) e aposicional (Grupo II) no cólon descendente. Foram utilizados 14 eqüinos adultos, sem raça definida, hígidos e com idade entre cinco e oito anos, submetidos à laparotomia de flanco esquerdo. Foram colhidas amostras de sangue e de fluido peritoneal nos períodos pré-jejum (-24 horas), pré-cirúrgico (0h) e às 6, 12, 18, 24, 48, 72, 96, 168, 336, 504, 672, 840, 1008 e 1176 horas de pós-operatório (p.o.) e realizadas as mensurações da concentração de fibrinogênio e da atividade da fosfatase alcalina. Nos dois grupos de equinos submetidos a enterotomias do cólon descendente foi possível evidenciar que as alterações nos parâmetros de fibrinogênio e atividade da fosfatase alcalina são mensuradas mais precocemente no fluido peritoneal do que no sangue circulante.Palavras-chave: Eqüinos. Fibrinogênio. Fosfatase alcalina. Cólon descendente SUMMARY: This study monitorated during the pre and postoperative periods the concentrations of plasma fibrinogen, serum alkaline phosphatase, fibrinogen and alkaline phosphatase in peritoneal fluid of horses submitted to enterorrafies of descending colon closed by full-thickness and simple continuous pattern (Group I) and directly apposition of the bowel wall using a single layer (Group II). Fourteen healthy, adult, undefined breed horses, between five and eight year-old were submitted a left flank laparotomy. Samples of blood and peritoneal fluid were collected at prefasting (-24 hours), preoperative (0 hour) and at 6, 12, 18, 24, 48, 72, 96, 168, 336, 504, 672, 840, 1008 and 1176 hours of postoperative periods for determination of fibrinogen concentration and the activity of alkaline phosphatase. Results of both groups from equines submitted to enterorrafies of descending colon showed that changes in fibrinogen and alkaline phosphatase parameters should be identified earlier in peritoneal fluid (6 hours p.o) than in blood samples.
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