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[1] The characteristics of the open vent activity of Villarrica volcano, Chile, were studied in detail by integrating visual observations of the lava lake, analysis of the seismic tremor, and measurements of SO 2 flux. The outgassing activity comprises a persistent gas plume emission from the bottom of the crater as well as frequent explosive events. Three main styles of bubble bursting were identified at the surface of the active lava lake: seething magma, small short-lived lava fountains, and Strombolian explosions. Seething magma consists of continual burst of relatively small bubbles (a few meters in diameter) with varying strength over the entire surface of the lava lake. Small lava fountains, seen as a vigorous extension of seething magma, commonly have durations of 20-120 s and reach 10-40 m high above the lava lake. Correlations between seismicity and visual observations indicate that the seismic tremor is mostly caused by the explosive outgassing activity. Furthermore, for different periods between 2000 and 2006, during which the activity remained comparable, the real-time seismic amplitude measurement system (RSAM) and SO 2 emission rates show a very good correlation. Higher SO 2 emissions appeared to be related to higher levels of the lava lake, stronger bubble bursting activity, and changes in the morphology and texture of the crater floor. Background (low) levels of activity correspond to a lava lake located >80 m below the crater rim, small and/or blocky morphology of the roof, seismic amplitude (RSAM) lower than 25 units, few volcano-tectonic earthquakes, and daily averages of SO 2 emissions lower than 600 Mg/d.

[1] Recently developed UV cameras offer improvement in remote sensing of volcanic SO 2 , with temporal resolutions of ∼1 Hz and synoptic plume views. Integrated UV camera and seismic measurements recorded in January 2009 at Fuego volcano, Guatemala, provide new insight into the system's shallow conduit processes. High temporal resolution SO 2 data reveal patterns of SO 2 emission rate relative to explosions and seismic tremor that indicate tremor and degassing share a common source process. Progressive decreases in emission rate appear to represent inhibition of gas loss from magma as a result of rheological stiffening in the upper conduit. Measurements of emission rate from two closely-spaced vents, made possible by the high spatial resolution of the camera (1024 × 1024 pixels), help constrain this model. This inter-disciplinary approach illuminates eruptive processes at Fuego and holds promise for gaining similar understanding at other volcanic systems.

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UDCA improved pruritus and biochemical cholestasis, and facilitated deliveries at term in ICP patients, with a higher birthweight compared with historical controls. The drug was well tolerated and no adverse effects were detected in their infants.

The efficacy and safety of ursodeoxycholic acid in the treatment of intrahepatic cholestasis of pregnancy was investigated in an open pilot study. Five patients received 1 gm/day of ursodeoxycholic acid during 20 days and another three patients received two identical periods of treatment separated by a 14-day interval free of the drug. Pruritus and serum levels of total bile salts and glutamic-pyruvic transaminase improved significantly during treatment with ursodeoxycholic acid. In the three patients who received two periods of treatment with ursodeoxycholic acid, pruritus and the laboratory alterations relapsed in the second week after the drug was discontinued, but they improved again when ursodeoxycholic acid was readministered. No adverse reactions were detected in the mothers or in their babies. All newborns were thriving normally during a follow-up period that lasted 5 mo after delivery. It is concluded that UDCA appears to be safe when administered in late pregnancy; its promising efficacy in the treatment of intrahepatic cholestasis of pregnancy should now be confirmed in controlled clinical trials.

The paroxysmal 2015 eruption of Volcán Villarrica (Chile) produced a 2.5 h long lahar, which descended more than 20 km within the Rio Correntoso/Turbio drainage and destroyed two small bridges. A three‐element infrasound array 10 km from the summit, and 4 km from the lahar's closest approach, was used to study the flow's progression. Array processing using cross‐correlation lag times and semblance places constraints on the lahar's dynamics, including detection of an initial flow pulse that traveled from 2 to 12 km at an average speed of 38 m/s. Subsequently, the lahar signal evolved to a relatively stationary infrasonic tremor located 10 to 12 km from the vent and adjacent to a topographic notch, through which sound may have preferentially diffracted toward the recording site. This study demonstrates the powerful capabilities of infrasound arrays for lahar study and suggests their potential application for future hazard monitoring.

Villarrica volcano outgasses through an open lava lake, with bubbles ranging in size from submillimeter to several meters, the largest of which produce strombolian bursting events that are visible from the crater rim. Thousands of shallow strombolian events identified through seismic waveform cross correlation were found to produce discrete and repetitive long-period seismic and infrasonic signals. We identified variations of up to 0.7 s in seismic-acoustic arrival delay times between April and July 2010 at a station~750 m from the vent, which we interpret as due to fluctuations in the level of lava lake. During time periods interpreted as having high lava lake levels, based on reduced time delays, interevent times were also reduced, and average seismic amplitude measurements, seismic and acoustic event energies, and volcano acoustic-seismic ratios were all high as compared to times when the lava lake was lower. The crater is also a source of nearly continuous, monotonic infrasonic tremor. We found that the peak frequency of this infrasonic tremor, typically around 0.5-1.0 Hz, was inversely correlated with seismic-acoustic delay times and therefore an indicator of lava lake level. We use this correlation to propose a new model for infrasonic tremor generation, namely, using crater geometry to approximate a Bessel horn. We interpret the two clearest cycles of elevated seismicity and lava lake level as due to an increase in exsolved gas, resulting from an injection of volatile-rich magma or an overturn in a deeper magma reservoir.