We demonstrate that congestive HF programmes should consider offering PD in hope of seeing better functional status, reduced morbidity and mortality, better quality of life as well as reduced health care costs.

COSMOS provides evidence of the association of serum phosphorus, calcium and PTH and mortality, and suggests survival benefits of controlling chronic kidney disease-mineral and bone disorder biochemical parameters in CKD5D patients.

Hyperphosphatemia has been associated with higher mortality risk in CKD 5 patients receiving dialysis. Here, we determined the association between the use of single and combined phosphate-binding agents and survival in 6797 patients of the COSMOS study: a 3-year follow-up, multicenter, open-cohort, observational prospective study carried out in 227 dialysis centers from 20 European countries. Patient phosphate-binding agent prescriptions (time-varying) and the case-mix-adjusted facility percentage of phosphate-binding agent prescriptions (instrumental variable) were used as predictors of the relative all-cause and cardiovascular mortality using Cox proportional hazard regression models. Three different multivariate models that included up to 24 variables were used for adjustments. After multivariate analysis, patients prescribed phosphate-binding agents showed a 29 and 22% lower all-cause and cardiovascular mortality risk, respectively. The survival advantage of phosphate-binding agent prescription remained statistically significant after propensity score matching analysis. A decrease of 8% in the relative risk of mortality was found for every 10% increase in the case-mix-adjusted facility prescription of phosphate-binding agents. All single and combined therapies with phosphate-binding agents, except aluminum salts, showed a beneficial association with survival. The findings made in the present association study need to be confirmed by randomized controlled trials to prove the observed beneficial effect of phosphate-binding agents on mortality.

No abstract

The unitary sense of self that exists across time is central to the human experience (Gallagher, 2000; Heatherton, Macrae, & Kelley, 2004). In this sense, the fundamental question on how humans understand and represent knowledge about themselves and others is attracting interest in social and cognitive neuroscience (Berkman, Livingston, & Kahn, 2017; Humphreys & Sui, 2016; Northoff, 2017). The concept of self-continuity is often defined as perceived associations of one's current self with past and future selves (Löckenhoff & Rutt, 2017). Northoff (2016a, 2017) has denoted this concept as a diachronic component linked to the awareness of the continuity of a person across time (i.e., "I am I" despite physical

We report a case of a large malignant solitary fibrous kidney tumor. A complete surgical resection of the primary tumor and peritoneal disease was carried out, and a histological examination confirmed the initial diagnosis. We describe and discuss the characteristics of this rare kidney neoplasm.

No abstract

El artículo que se presenta tiene como objetivo ofrecer una metodología para la elaboración de preguntas que desarrollen la comprensión de problemas matemáticos en la Enseñanza Primaria. El principal aporte de la investigación a la Didáctica de la Matemática reside en la metodología que se ofrece, la cual se sustenta en la reconceptualización de los problemas matemáticos como textos y la asunción de la resolución de problemas como proceso de comprensión textual. La efectividad de la metodología fue valorada mediante su implementación en la práctica educativa de la Escuela Vocacional de Arte "Luis Casas Romero" durante el curso 2010 – 2011.