al., 1992). In contrast to the many reports of extragonadal germ cell tumours, there have been only a few reports of testicular tumours (Carroll et al., 1988;Dexeus et al., 1988;Reddy et al., 1991).No September 1994 cinoma of the breast were observed. which was similar to the expected incidence in women (Price et al.. 1985).The many case reports of KS and cancer are suggestive of a relationship. but do not allow any estimates of the relative risk of cancer in men with KS. Such data are important to help in prenatal counselling and to physicians who take care of patients with KS. This study presents the cancer incidence in a large cohort of men with KS with a virtually complete follow-up.
Materials and methodsThe stud) cohort The Danish Cytogenetic Register was founded in 1968 and has collected information on chromosomal abnormalities diagnosed in Denmark (Nielsen. 1980). The register is based upon reports from seven cytogenetic laboratories throughout the country. It is assumed that the register has a virtually complete coverage of the constitutional chromosomal abnormalities diagnosed in Denmark since 1961.A total of 707 men with a diagnosis of KS were registered in the Cytogenetic Register by December 1992. Two persons were not Danish residents and were excluded from the cohort. Two persons were excluded because of insufficient follow-up data. Six persons were excluded because of an additonal somatic trisomy (five with trisomy 18 and one with trisomy 21). One of the prenatally diagnosed patients had a twin brother with normal karyotype and had to be excluded from the study because the case person could not be identified. Accordingly, the final study cohort consisted of 696 men with KS, of whom 20 were diagnosed prenatally.
Objectives of the paper are to provide dichotomous keys for the identification of ophidiiform genera. For each genus a brief account is presented including synonymy, a short diagnosis, a list of species, distribution, references, when possible comments on relationships, and for most an outline drawing. The genera are organized into an hierarchical classification which divides them into two suborders, Ophidioidei, which contains oviparous fishes with a high anterior nostril, and Bythitoidei which contains viviparous fishes with a low anterior nostril. Ophidioidei is divided into two families. Carapidae, with a vexillifer larval stage, has two subfamilies: Pyramodontinae with two genera and Carapinae with four. Ophidiidae has four subfamilies: Brotulinae, with a single genus; Brotulotaeniinae (new family) with a single genus; Ophidiinae, the cusk eels, with eight genera in two tribes; and Neobythitinae, with 38 genera (Epetriodus and Spottobrotula are new genera based on new species from the Indian Ocean) in two tribes. Bythitoidei contains two families, one of which, Aphyonidae has five genera characterized by many neotenic features. Bythitidae is divided into the free-tailed Brosmophycinae with 13 genera in two tribes and Bythitinae with 15 genera.
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