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(Glaser, 1972). Although choreoathetosis has been described (Peters, 1962;Logan and Freeman, 1969;Kooiker and Sumi, 1974;McLellan and Swash, 1974), only a few cases have been documented adequately. During the last two years we have seen involuntary movements in four patients, two of whom presented with severe choreoathetosis. These patients are described in the following case reports. (Accepted 5 September 1974.) 225 signs. A left carotid arteriogram showed a shift to the right of the anterior cerebral artery, and a pneumoencephalogram (AEG) showed displacement of the ventricles to the right without significant alteration of ventricular size or shape. A gross unilateral abnormality over the left hemisphere posteriorly was seen on EEG. The pathological significance of these findings was uncertain. His fits were bizarre in pattern and were asymmetrical, being more marked on the right, and being accompanied by transient aphasia. A three day course of corticotrophin (ACTH) was without effect, but when pheneturide 400 mg daily was started the fits appeared to decrease in frequency and severity. However, four days after starting this drug, he developed marked choreoathetoid movements involving head, neck, and upper limbs. Although it was felt at the time that this was due to the same process as that causing the fits, the movements disappeared when pheneturide was withdrawn.

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