ObjectiveTo describe epidemiological aspects of suicide mortality in a 10-year time series.

O presente trabalho busca relatar a história da Medicina de Família e Comunidade (ex-Medicina Geral Comunitária) no Brasil, bem como da sua entidade nacional representativa, sua interação com o Programa de Saúde da Família e o estabelecimento de propostas para o futuro

Rio Grande do Sul State has the highest suicide rates in Brazil. Previous studies have suggested a possible role of agricultural activities, especially tobacco farming, where pesticide use is intensive. An ecological study was designed to assess associations between age-adjusted suicide rates based on death certificates and socioeconomic and agricultural factors. Suicide rates in males and females were inversely associated with schooling level and directly associated with divorce/marital separation. Rates for men were higher in areas where traditional Protestant religious were more prevalent, and rates for women were lower in areas with a higher proportion of single-inhabitant households. Multivariate analyses showed no associations between increased suicide rates and any of the agricultural variables. These results confirm the role of socioeconomic determinants of suicide, but do not support the hypothesis of a specific role of agricultural practices.

RESUMO O objetivo do estudo foi caracterizar o perfil e a trajetória profissional dos egressos dos Programas de

Zwei Gruppen von Kaninchen erhielten entweder Hydroxyäthylstärke von McGaw (Volex®) oder Dextran (Macrodex®, Pharmacia AB, Uppsala) in der Dosierung von 50 ml/kg KG in Form von 10 täglich verabreichten Infusionen. Die Serumspiegel der beiden Expander wurden über ein Jahr durch 14tägige Messungen verfolgt. Bei einigen Tieren wurden die Konzentrationen der Expander im Lebergewebe 1 Jahr nach Infusionsende gemessen. Histopathologische Untersuchungen erfolgten zum Teil mittels Leberbiopsie von Infusionsende bis zu 1 Jahr danach. Die Ergebnisse zeigen, daß Hydroxyäthylstärke (Volex®) während eines Jahres nicht vollständig abgebaut und eliminiert wird und zu langanhaltenden morphologischen Veränderungen führt, während Dextran (Macrodex®) nach 2 Monaten chemisch im Serum nicht mehr lïachweisbar ist.