Abuse of blood donation is common in Calabar and Nigeria. Research on blood donors has focused on the erythrocyte and iron-related parameters, without considering the other cell lines of the donors. This study examined the effect of frequent blood donations on leucocytes and thrombocytes. One hundred and eighty four subjects aged 18-35 years were used for this study. The subjects were divided into 5 groups thus; 35 (19%) control group, 32 (17.4%) of first time donors, 35 (19%) of second time donors, 41 (22.3%) of third time donors and 41 (22.3%) of fourth time donors. Their full blood counts were evaluated using complete automated cell counter and values obtained were statistically analyzed. Results showed that 63% of the donors were commercial blood donors. Haematocrit (Hct) of first (41.9±0.66%), second (40.1±0.47%), third (39.1±0.54%) and fourth (33.3±0.56%) time male donors decreased progressively as number of times of donation increased, compared with control (43.9±0.55%). Total White Blood Cell (WBC) count significantly (p<0.001) decreased in first, third and fourth time donors, compared with control. Monocytes, granulocytes and platelet counts decreased progressively with repeated blood donations. Lymphocytes increased progressively following repeated blood donations. We therefore, conclude that, serial blood donation decreases Hct, WBC (monocyte and granulocyte) and platelet counts in males and increases lymphocyte count.
is an International, peer-reviewed scientific journal that publishes original article in experimental & clinical medicine and related disciplines such as molecular biology, biochemistry, genetics, biophysics, bio-and medical technology. JMS is issued four times per year on paper and in electronic format.
Surgical operations constitute an integral part of medical management of different health challenges. Developing countries suffer from under-reporting of health conditions even when such conditions are fairly common in occurrence. This study observed common surgical cases with a view to highlighting possible associations with gender. A retrospective cross-sectional descriptive approach was adopted. A total of 626 cases presenting for surgical review between a two-year periods from September 2020 to August 2022 at University of Calabar Teaching Hospital, Calabar in Nigeria were reviewed. Data analysis to test for gender association was carried out using chi-square analysis on SPSS 22.0 at 95% confidence level with p-value of ≤ 0.05. The highest frequency of 56% was recorded for breast tumour. This was followed by hernia and goitre which accounted for 20% and 15 of surgical cases respectively. Lesser frequencies were observed for lipoma (4%), appendicitis (2%) and fistula (2%). The least among the commonly observed cases was testicular torsion which was recorded to be 1%. Breast tumour and goitre were significantly higher in females compared to males, while hernia was seen to be significantly higher in males compared to females. Testicular torsion occurred solely in males. This study concludes that significant gender associations exist in the distribution of surgical cases at the study centre. While female preponderance was observed for breast tumour and goitre cases, hernia was prevalent among the males.
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