In recent years heterocyclic Schiff base metal complexes attract more attention in biological application and also showing interesting co-ordination chemistry. In this research article a novel heterocyclic methyl-substituted pyridine Schiff base transition metal complexes of Fe(III), Co(III), Cu(II), and Ni(II) have been design and synthesized by reacting metal acetate or metal salts (FeCl3, CoOAc, CuOAc, NiOAc), with substituted heterocyclic ligand. All newly synthesized metalcomplexes were characterized by spectroscopic data and screened for elemental analysis, FT-IR, ESR, Magnetic susceptibility and TGA. The Electronic spectra and magnetic susceptibility measurements indicates that square planer and octahedral geometry of these complexes also suggest their structure in which (N, O) group acts as bidentate ligand. The thermal stability, decomposition rate and thermodynamic parameters of synthesized metal complexes were calculated by Freeman Carroll method. Also the biostatistical data of antimicrobial and anti-oxidant activities of synthesized metal complexes indicates moderate to good results. Graphic abstract
Novel classes of heterocyclic Schiff base ligand were prepared from the condensation of 2-methoxy benzaldehyde and 2-amino 4-methyl pyridine in absolute ethanol in presence of catalytic amount of dilute HCl. The resulted novel class ofheterocyclic ligand was treated with metal salt or acetate results in the formation of Fe (III), Co (III), Ni (II) & Cu (II)complexes. All newly synthesized resulted ligand its metal complexes were characterized by elemental analysis and FTIR,Magnetic susceptibility, Antimicrobial, Antioxidant, ESR spectrum for Copper complex in DMF solvent recorded atroom temperature. The Electronic spectra and magnetic susceptibility measurements indicates that square planer andoctahedral geometry of these complexes also suggest their structure in which (N, O) group acts as bidentate ligand. Thethermal stability, decomposition behavior has been investigated by using thermo gravimetric analysis at heating rate 10°Cper minute with nitrogen atmosphere and their and kinetic parameter was also calculated by using Freeman Carrollmethod. Screening results of antimicrobial, antioxidant activity of transition metal complexes shows good antibacterialand antifungal activity and excellent antioxidant activity.
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