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E 2 2 7What ' s known on the subject? and What does the study add? It is known that timed intercourse that is planned to coincide with ovulation causes stress in women. In men premature ejaculation is more common than delayed ejaculation.

During the fertile window of a woman's menstrual cycle, the effect of impending timed intercourse (TI) on the psychological well-being and behavior of male partners has not been thoroughly investigated, despite the fact that men comprise one half of each couple endeavoring to achieve natural conception. This prospective study consisting of 439 men was conducted during a 3-year period between July 1, 2008, and June 30, 2011. Various characteristics were evaluated, including newly acquired erectile dysfunction (ED); extramarital sex (EMS); intake of soft drinks (SD); levels of hormones, such as follicle-stimulating hormone (FSH), luteinizing hormone (LH), testosterone (T), prolactin, and estradiol (E2); and semen parameters. A total of 188 men (42.8%) experienced ED and 47 men (10.7%) engaged in EMS. As the number of TI episodes increased, the number of men with ED and EMS and those who wanted to avoid TI also increased (all, P , .0001). All 47 men who reported EMS experienced ED with their spouses. Men who consumed SDs produced significantly smaller volumes of semen (P 5 .0363). Among the hormones investigated, the levels of LH, T, and E2 were significantly lower in men with ED (all, P , .05) whereas the level of FSH was higher in contrast to E2, which was significantly higher in men who had EMS (both, P , .01). TI imposes a great deal of stress on male partners evoking ED and, in some cases, causing these men to seek EMS. Physicians and clinicians should acknowledge the potential harmful effects of TI on men. Furthermore, both female and male partners should also be cautioned about the increased possibilities of ED and EMS as TI incidents increase.

Chronic prostatitis/chronic pelvic pain syndrome (CP/ CPPS) is a common condition that adversely affects men across a wide range of ages. A number of pharmacologic and nonpharmacologic therapies for CP/CPPS have been investigated. Our study aimed to evaluate the prevalence of CPPS in Korean men in their thirties and to investigate the effect of CPPS and medical treatment on semen quality. Of 314 men with prostatitis, 74 patients with CPPS class IIIA (23.6%) were eligible for the study; these patients underwent combined a-blocker and cyclo-oxygenase 2 inhibitor therapy. These 74 men were prospectively studied at a medical center in Seoul, Korea. A number of parameters, including ejaculations per month, semen variables, and the levels of hormones (such as follicle-stimulating hormone, estradiol [E 2 ], luteinizing hormone [LH], testosterone, and prolactin) were evaluated. The mean number of ejaculations per month, the mean number of daily hours spent sitting at work, smoking, body mass index, LH and E 2 levels, and semen parameters all showed significant differences (P , .0001) between the study patients and the controls. The combined regimen was effective in improving all aspects of semen quality except morphology (P , .05). CPPS class IIIA, which is notably prevalent among Korean men in the fourth decade of life, affects semen quality and poses a challenge to fertility. Proper treatment of CPPS class IIIA results in improved semen quality. Men with CPPS therefore require proper evaluation and treatment by andrologists/ urologists before planning a natural conception.Key words: CPPS, hormones, zaltoprofen, alfuzosin. J Androl 2012;33:876-885 C hronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is a prevalent disease for which there is no standard therapy. The disease is common and adversely affects men across a wide range of ages. The reported prevalence of CP/CPPS ranges from 2% to 10%, with the overall lifetime prevalence estimated to be 9% to 16% (Nickel, 2007). CP/CPPS is a clinical syndrome characterized by pain in the perineum, pelvis, suprapubic area, or external genitalia, with variable degrees of voiding disturbance. A number of pharmacologic and nonpharmacologic CP/CPPS therapies have been investigated. In Korea, an increased incidence of young men with CPPS symptoms without any evidence of infection has recently been seen. Our study found that 23.6% of a group of 314 male patients with CPPS had symptoms characteristic of CPPS class IIIA. From a variety of treatment modalities, combined a-blocker and cyclo-oxygenase 2 (COX2) inhibitor therapy was selected for our study participants. To our knowledge, this is the first report on the prevalence of CPPS class IIIA in young Korean men endeavoring to achieve natural conception and the first report that describes the effects of CPPS, medical intervention, and lifestyle factors on the semen quality and reproductive hormone levels of men in their thirties. Materials and Methods SiteThe evaluation site comprised the andrology service and prostat...

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