Several epidemiologic studies have shown elevated uric acid levels to predict increased risk of cardiovascular events. Few studies have addressed the value of this biomarker across the whole spectrum of patients with ACS (Acute Coronary Syndrome) especially in Indian settings. Thus, the aim of this study was investigate whether there is an association between serum uric acid level with CAD (Coronary Artery Disease) risk factors its and severity in ACS patients. Material and methods: This cross -sectional study included 100 consecutive patients admitted with acute coronary syndrome in the cardiology and medicine department of the institution. The presence and severity of CAD was determined by the following clinical vessel score; Absent: no coronary lesions, 1 vessel, 2 vessel and 3 vessel -disease based on the number of coronary arteries involved. The correlation of serum uric acid levels with CAD risk factors and the severity of CAD in the ACS patients was analysed statistically. Results: There was a significant association between uric acid and the coronary angiographic findings (P<0.001). The patients in the hyperuricemia group had more number of coronary vessels involved than the other group.
Conclusion:The serum uric acid level is correlated with the presence and severity of CAD by coronary angiographic findings (P<0.001) in the acute coronary syndrome patients. Uric acid being an inexpensive and easily available biochemical marker, it will be of much use in settings with limited resources. Serum uric acid may be used to predict the severity of CAD.
Medical research is an important aspect of medical education and is required to maintain quality. Funding can assist a researcher in doing extensive research in a certain area by boosting study variables, sample size and use of sophisticated state-of-the-art equipments. India’s funding for health research is limited, and only a small percentage of that is used for public health research. Many health professionals have a lot of great ideas for health-related research but do not know where to start looking for financing. A review was created to help medical and nursing professionals to find the correct funding source for their research. There are many governments’ organisations in India, which provide funds for research, grants and higher learning research fellowships. We tried to give an overview of some organisations with their benefits. This review includes the Indian Council of Medical Research (ICMR), Defence Research and Development Organisation (DRDO), Science and Engineering Research Board (SERB), India Alliance, Department of Science and Technology (DST), Department of Biotechnology (DBT), Council of Scientific and Industrial Research (CSIR), Department of Health Research (DHR), Trained Nurses Association of India (TNAI), and the Nursing Research Society of India (NRSI). This review makes aware health professionals to the funding agency as well as the time of funding and fellowship application.
Goodpasture disease is an anti–glomerular basement membrane (anti-GBM) disease that manifests as progressive glomerulopathy and alveolar hemorrhage. Our case was a 68-year-old female who presented with decompensated liver disease (DCLD) with no prior history suggestive of liver disease. She had dyspnea, bilateral pitting edema, icterus with normal renal parameters, and elevated liver enzymes. Ultrasonogram revealed shrunken liver, ascites, and portal hypertension with normal renal cortex echogenicity. Over the next three days, she developed progressive oliguria, hematuria, and breathlessness, with arterial blood gas showing hypoxia with acidosis and hyperkalemia. Bronchoscopic alveolar lavage was suggestive of hemorrhagic fluid. The patient succumbed to the disease in 24 hours. Anti-GBM antibodies came positive by immunofluorescence assay which confirmed the diagnosis of Goodpasture syndrome. Unusual presentation of DCLD in our case resulted in a delay in diagnosis that could have been crucial in altering the outcome.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.