Through the method of integrated molding and simple spraying, our PNGA can be easily prepared, which exhibit solar steam generation efficiency of 93.8% under 1 sun and excellent barrier properties for pollutant, thus increase practical possibilities.
As one of the foundations of existential positive psychology, self-transcendence can bring positive intrapersonal and interpersonal outcomes, especially in the COVID-19 era in which people are suffering huge mental stress. Based on Schwartz's theory of human basic values, the current study combines variable-centered and person-centered approaches to examine the relationships between adolescents' values and mental health across two regions in China. The results generally showed that (1) both self-enhancement and conservation values were positively correlated with depression and loneliness, while both self-transcendence and openness to change values negatively correlated with depression and loneliness. The results also showed that (2) there were four value clusters (i.e., self-focus, other-focus, anxiety-free, undifferentiated), and, compared to adolescents in the self-focus and undifferentiated values cluster, all adolescents in the anxiety-free values cluster reported lower depression and loneliness, while all adolescents in the other-focus values cluster reported higher depression and loneliness. The differences between the two regional groups only emerged in depression. Specifically, adolescents in Shanghai have higher levels of depression than adolescents in Qingdao. This study provides some evidence for the new science of self-transcendence among adolescents and also sheds light on how we may improve the level of mental health during the COVID-19 era.
Background Targeting the long non-coding RNAs (LncRNAs)-microRNAs (miRNAs)-mRNA competing endogenous RNA (ceRNA) networks has been proved as an effective strategy to treat multiple cancers, including oral squamous cell carcinoma (OSCC). Based on this, the present study identified a novel LncRNA SNHG16/miR-17-5p/CCND1 signaling pathway that played an important role in regulating the pathogenesis of OSCC. Methods The expression levels of cancer-associated genes were examined by Real-Time qPCR and Western Blot at transcriptional and translated levels, respectively. CCK-8 assay was performed to determine cell proliferation, and cell apoptosis ratio was measured by the Annexin V-FITC/PI double staining assay. Transwell assay was performed to examine cell migration, and dual-luciferase reporter gene system assay was used to validate the ceRNA networks. Results LncRNA SNHG16 and CCND1 were upregulated, while miR-17-5p was downregulated in OSCC tissues and cell lines, compared to their normal counterparts. Also, miR-17-5p negatively correlated with both LncRNA SNHG16 and CCND1 mRNA, but LncRNA SNHG16 was positively relevant to CCND1 mRNA in OSCC tissues. By performing the gain- and loss-of-function experiments, we noticed that LncRNA SNHG16 overexpression aggravated the malignant phenotypes, such as cell proliferation, viability, migration and epithelial-mesenchymal transition (EMT) in OSCC cells, while LncRNA SNHG16 knock-down had opposite effects. Furthermore, our dual-luciferase reporter gene system evidenced that LncRNA SNHG16 sponged miR-17-5p to upregulate CCND1 in OSCC cells, and the inhibiting effects of LncRNA SNHG16 ablation on OSCC progression were abrogated by both downregulating miR-17-5p and overexpressing CCND1. Finally, the xenograft tumor-bearing mice models were established, and our data validated that LncRNA SNHG16 served as an oncogene to promote tumorigenicity of OSCC cells in vivo. Conclusion Taken together, targeting the LncRNA SNHG16/miR-17-5p/CCND1 axis hindered the development of OSCC, and this study provided potential diagnostic and therapeutic biomarkers for OSCC in clinic.
The exploitation of high efficiency non-precious electrocatalysts for oxygen reduction reaction (ORR) is of great significance for large-scale commercialization of next-generation fuel cells. Herein, we report the synthesis of conjugated polymers (CP) based on poly(o-phenylenediamine) as a nitrogen-containing precursor for preparation of Co-and FeCl 3 -doped N-rich carbon for ORR (abbreviated as Co-OPD and FeCl 3 -OPD). Based on their high specific surface, excellent porosity and large pyridine nitrogen content, the as-synthesized FeCl 3 -OPD, which is prepared at a pyrolysis temperature of 800 C (FeCl 3 -OPD-800), exhibits highest catalytic activity among the resulting electrocatalysts, that is, it possesses a largest half-wave potential of 0.854 V (≈20 mV more positive than Pt/C), a high diffusion limiting current density of 3.95 mA cm −2 and a biased 4e − reaction pathway. In addition, this catalyst also discloses an excellent methanol tolerance and better durability than the commercial Pt/C. Taking advantage of their high ORR activity as well as simple fabrication which makes it possible using inexpensive FeCl 3 as both catalysts for CP precursors and metal dopant for FeCl 3 -OPD only by a one-step pyrolysis, thus such FeCl 3 -OPD may hold great potentials as promising alternative of precious metal catalysts for next generation fuel cells.
Insulation materials with high sealing, high insulation, high elasticity, and other characteristics are widely used in the power industry. In this paper, the terahertz time-domain reflection spectrum of cable insulation materials is studied, the optical parameters of cable insulation materials are extracted to characterize the aging state of cable insulation materials, the terahertz time-domain reflection signal of insulation materials with different degrees of aging is tested, and the terahertz reflection spectrum of insulation sheaths is analyzed. The relationship between the aging degree and absorption coefficient in terahertz time-domain spectral reflection mode is obtained. There are obvious differences in the absorption characteristics of cable insulation materials with different degrees of aging in the terahertz band. The longer the aging time is, the greater the absorption coefficient is and the lower the refractive index is. Terahertz time-domain reflectometry plays a role in cable protection with high detection accuracy in the characterization of cable insulation materials.
The development of non-precious metal catalysts with high efficiency and superior reaction durability for oxygen reduction reaction (ORR) is of great importance for construction of next-generation fuel cells. Herein, we report the preparation of in-situ nitrogen-doped carbon nanotube electrocatalysts (PPy-NCNTs) which were prepared by the pyrolysis of one-dimensional nanotubelike polypyrrole conjugated polymers precursor (PPy-Tubes) synthesized by oxidative polymerization and self-assembly method. The as-prepared PPy-NCNTs show good ORR performance, e.g., its half-wave potential reaches 0.826 V. In order to further improve the ORR performance of PPy-NCNTs, we prepared the Co-N co-doped carbon nanotube materials (Co-N-PPy-NCNTs) with different Co contents by adding cobalt nitrate into the polymerization solution during synthesis of PPy nanotube followed by a pyrolysis treatment. Comparatively, the Co-N-PPy-NCNTs have better ORR performance than that of PPy-NCNTs with a half-wave potential of 0.830 V, a biased 4ereaction pathway, and better stability and methanol tolerance (high than Pt/C catalysts in the methanol tolerance test and the durability test). Taking advantages of its simple and cost-efficient preparation, high ORR performance and superior stability and methanol tolerance, the Co-N-PPy-NCNTs should be a kind of ideal candidate as an alternative to the precious metal platinum-based catalysts for fuel cells.
To ensure detection accuracy, the focus of the terahertz lens is required to be located on the surface of the workpiece in the process of terahertz imaging detection, and the outgoing optical axis of the lens is also required to be perpendicular to the surface of the workpiece. Therefore, when imaging curved samples, a 6-degree freedom manipulator is generally used to drive the terahertz lens, and the lens realizes non-destructive testing along the workpiece surface. The mechanical arm is required to drive the terahertz lens to move along the rotation curve in a two-dimensional plane when the mechanical arm is used to detect the power insulator of the rotating structure. This paper focuses on the path planning of the manipulator, that is, the curve is divided into several connected straight lines and arcs, and the manipulator moves continuously in each characteristic line segment. The D-H dynamic model of the manipulator was established to analyze the joint velocity and acceleration to ensure the stability of the moving process.
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