A novel visible-light-photocatalytic deuterated thiomethylation/methylselenation of aryldiazonium salts utilizing S/ Se-methyl-d 3 sulfonothioate has been developed. The mild conditions and the various functional groups provide a green protocol for the efficient and rapid introduction of the S-CD 3 or Se-CD 3 group with useful levels of deuterium content (>91% D). Trideuteromethyl sulfoxides have also been successfully chemoselectively observed by simple atmospheric changes under photocatalytic conditions.
An
iron–sulfur complex formed by the simple mixture of FeCl3 with S3
•– generated in
situ from K2S is developed and applied to selective aerobic
oxidation of terminal alkenes. The reaction was carried out under
an atmosphere of O2 (balloon) and could proceed on a gram
scale, expanding the application of S3
•– in organic synthesis. This study also encourages us to explore the
application of an Fe–S catalyst in organic reactions.
A photocatalytic synthesis of thieno[3,4-c]quinolin-4(5H)-ones/selenopheno[3,4-c]quinolin-4(5H)-ones using diphenyl disulfide or
diphenyl diselenide
as sulfur or selenium sources was developed. Two C–S/Se bonds
and one C–C bond were constructed simultaneously without transition
metals and other additives.
An efficient transition-metal-free decarboxylative cyclization of N-arylacrylamides with 2,2-difluoro-2-(phenylthio)acetic acid for the construction of thiodifluoroindoleone derivatives is described. This strategy features stable and readily available substrates, mild reaction conditions, and transition-metal-free catalysts. Notably, this protocol has successfully applied to synthesis of gem-difluoroalkenes, which exist in numerous biologically active compounds.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.