Two-dimensional (2D) MXenes have recently been shown to be promising for applications in anticancer photothermal therapy (PTT), owing to their outstanding photothermal performance. However, as with the other inorganic 2D nanomaterials, the MXene-based nanoplatforms lack the appropriate biocompatibility and stability in physiological conditions, targeting capability, and controlled release of drug, for cancer therapy. Fabricating a smart MXene-based nanoplatform for the treatment of cancer therefore remains a challenge. In this work, composite hydrogels based on cellulose and TiC MXene, were synthesized for the first time. We have shown that the cellulose/MXene composite hydrogels possess rapid response near-infrared-stimulated characteristics, which present as a continuous dynamic process in water. As a result, when loaded with the anticancer drug doxorubicin hydrochloride (DOX), the cellulose/MXene hydrogels are capable of significantly accelerating the DOX release. This behavior is attributed to the expansion of the pores within the three-dimensional cellulose-based networks, triggered by illumination with an 808 nm light. Capitalizing on their excellent photothermal performance and controlled, sustained release of DOX, the cellulose/MXene hydrogels are utilized as a multifunctional nanoplatform for tumor treatment by intratumoral injection. The results showed that the combination of PTT and prolonged adjuvant chemotherapy delivered using this nanoplatform was highly efficient for instant tumor destruction and for suppressing tumor relapse, demonstrating the potential of the nanoplatform for application in cancer therapy. Our work not only opens the door for the fabrication of smart MXene-based nanocomposites, along with their promising application against cancer, but also paves the way for the development of other inorganic 2D composites for applications in biomedicine.
Three-dimensional (3D) graphene aerogels (GA) show promise for applications in supercapacitors, electrode materials, gas sensors, and oil absorption due to their high porosity, mechanical strength, and electrical conductivity. However, the control, actuation, and response properties of graphene aerogels have not been well studied. In this paper, we synthesized 3D graphene aerogels decorated with Fe3O4 nanoparticles (Fe3O4/GA) by self-assembly of graphene with simultaneous decoration by Fe3O4 nanoparticles using a modified hydrothermal reduction process. The aerogels exhibit up to 52% reversible magnetic field-induced strain and strain-dependent electrical resistance that can be used to monitor the degree of compression/stretching of the material. The density of Fe3O4/GA is only about 5.8 mg cm(-3), making it an ultralight magnetic elastomer with potential applications in self-sensing soft actuators, microsensors, microswitches, and environmental remediation.
PSS-GO:NH3 layer, and partially to the better matched energy-level-alignment at the perovskite interface. Furthermore, the device was shown to be more stable in the ambient condition, which is clearly associated with the improved peovskite structure stability by the GO:NH3 layer observed by the GIXRD measurements. All these achievements will promote more applications of chemically modified graphene oxide interfacial layer in the PSCs as well as other organic multilayer devices.
Here, we report fabrication of two-dimensional (2D) lead monoxide (PbO) nanosheets by facile liquid phase exfoliation. The as-prepared 2D PbO nanosheets have circle and cut-circle shapes with a lateral dimension range of 200−400 nm and a thickness range of 10−15 nm and exhibit dominant β-crystals with a robust chemical stability under ambient conditions. As a building block, the 2D PbO has been developed for photoelectrochemical (PEC)-type photodetectors that exhibited excellent as well as tunable photoresponse behaviors under illuminations of ultraviolet−visible lights. The first-principles density functional theory calculations further show that the band gap (E g ) of 2D PbO can be tuned by external electric field with a significant Stark effect. Moreover, differing from most transition metal dichalcogenide (TMD) materials, the 2D PbO structure, whose lowest empty states are dominated by the lead p orbitals, is exposed, which means that orbital modification of 2D PbO is accessible. Consequently, the E g of PbO can be decreased in the KOH electrolyte by a possible Pb−OH interaction, thus, broadening its absorption range for photodetection applications. In addition, the photoresponse behavior of 2D PbO-based photodetectors has long-term stability. This work may open the way for development of 2D PbO nanomaterials with promising applications.
Precisely regulating water and molecule permeation through membranes is of crucial significance in broad domains such as water filtration and smart reactors. Comparing with routine stiff membranes, stimuli‐response polymers endow porous membranes with various gating properties, but most of these membranes have only one‐way gating performance, that is, either positive or negative. Here poly(N‐isopropylacrylamide) (PNIPAM) grafted graphene oxide (GO) membranes with reversible positive/negative gating regularity are constructed by simply tuning the molecule grafting density. The water and small molecule permeance of the membranes can be regulated by adjusting environment temperature. Based on this tunable thermoresponsive gating regularity, a bidirectional fluidic controlling system is designed by integrating a positive membrane and a negative membrane, which can be employed as a self‐adaptive gating reactor. This strategy provides an insight into constructing smart gating membranes with extraordinary properties, showing promising applications in micro/nanofluidic valves and temperature sensitive biochemical reactors.
Flexible graphene fibers (GFs) with an ultimate elongation of 20% and a tensile strength up to 150 MPa were prepared by a facile low temperature chemical reduction-induced self-assembly method using graphene oxide (GO) suspensions reacted with vitamin C and then dried at room temperature.
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