Pulse diagnosis is an irreplaceable part of traditional Chinese medical science. However, application of the traditional pulse monitoring method was restricted in the modernization of Chinese medical science since it was difficult to capture real signals and integrate obscure feelings with a modern data platform. Herein, a novel multichannel pulse monitoring platform based on traditional Chinese medical science pulse theory and wearable electronics was proposed. The pulse sensing platform simultaneously detected pulse conditions at three pulse positions (Chi, Cun, and Guan). These signals were fitted to smooth surfaces to enable 3-dimensional pulse mapping, which vividly revealed the shape of the pulse length and width and compensated for the shortcomings of traditional single-point pulse sensors. Moreover, the pulse sensing system could measure the pulse signals from different individuals with different conditions and distinguish the differences in pulse signals. In addition, this system could provide full information on the temporal and spatial dimensions of a person’s pulse waveform, which is similar to the true feelings of doctors’ fingertips. This innovative, cost-effective, easily designed pulse monitoring platform based on flexible pressure sensor arrays may provide novel applications in modernization of Chinese medical science or intelligent health care.
In situ harvesting undersea energy is a vital method for undersea detector to realize its long‐term and real‐time undersea research. Herein, inspired by the fins with excellent hydrodynamic characteristic and the triboelectric nanogenerator (TENG) with the merits of light‐weight and high‐efficiency at low frequency, an energy harvesting device is designed to harvest undersea energy by bionic‐fin‐structure assisted with multilayer‐structured triboelectric nanogenerator (BFM‐TENG). The good design of geometry and structure enable BFM‐TENG to harvest energy efficiently by the driving of water‐flow from multidirections. Besides, based on the multiarea contact structure and ultrathin dielectric material, the BFM‐TENG could achieve a peak power density of 444 W m−3 under ideal test condition, which is about 1–2 orders of magnitude higher than that of previous work for harvesting wave energy. The findings not only provide a new in situ undersea energy harvesting method for undersea detectors to realize the real‐time, long‐term, and self‐powered undersea research, but also provide a potential strategy to achieve large‐scale undersea energy harvesting.
It is highly important to understand the heterogeneous wettability properties of porous media for enhanced oil recovery (EOR). However, wettability measurements are still challenging in directly investigating the wettability of porous media. In this paper, we propose a multidimensional nuclear magnetic resonance (NMR) method and the concept of apparent contact angles to characterize the heterogeneous wettability of porous media. The apparent contact angle, which is determined by both the wetting surface coverage and the local wettability (wetting contact angles of each homogeneous wetting regions or wetting patches), is first introduced as an indicator of the heterogeneous wettability of porous media using the NMR method. For homogeneously wetting patches, the relaxation time ratio T1/T2 is employed to probe the local wettabiity of wetting patches. The T2 − D is introduced to obtain the wetting surface coverage using the effective relaxivity. Numerical simulations are conducted to validate this method.
Murine models of cardiac disease are becoming an important tool for studying pathophysiological processes. Development of methods to accurately assess ventricular function are therefore important. The purpose of this study was to evaluate the feasibility of echocardiographic assessment of segmental wall motion abnormalities in a murine model of myocardial infarction. Two-dimensional contrast (C+) and noncontrast (C-) echocardiography were performed in 76 awake mice 2 days before and 2 days after left coronary ligation. The short-axis images obtained with two-dimensional echocardiography and corresponding postmortem cross-sectional histological samples stained with Evans blue dye were each divided into 16 segments, and all matched segments were examined for correlation between wall motion abnormalities and myocardial hypoperfusion. With the use of contrast enhancement, the number of visualized segments was significantly increased (base: C- 86%, C+ 98%; midpapillary: C- 57%, C+ 89%; apex: C- 30%, C+ 74%). Agreement between echocardiographically assessed regional wall motion abnormalities and pathologically determined hypoperfusion in basal, midpapillary, and apical levels were 90%, 93%, and 93%, respectively. Agreement between echocardiographically normal wall motion and pathologically normal findings in basal, midpapillary, and apical levels were 99%, 88%, and 71%, respectively. Thus echocardiographic assessment of segmental wall motion in awake mice was feasible and the accuracy was improved with the use of a contrast agent.
In this study, we evaluated the value of diffusion-weighted imaging (DWI) and magnetic resonance (MR) spectroscopy imaging (MRSI) combined with computed tomography (CT) and conventional MR imaging (MRI) in the diagnosis of Kimura disease (KD). The clinical data and CT and MRI findings of 5 patients with KD proven by histopathologic examination were retrospectively reviewed. Diffusion-weighted imaging and MRSI were performed at 1.5 T in 3 patients with KD. Apparent diffusion coefficient (ADC) values and the choline/creatine ratio of the lesions were compared with those of the contralateral normal parotid glands. All imaging results were compared with histopathologic findings. The typical features of KD were subcutaneous lesions, continuously infiltrative parotid lesions with or without intraparotid lymphadenopathies, and reactive cervical lymphadenopathies on CT and conventional MRI. On DWI, the ADC values of all subcutaneous and infiltrative parotid lesions were higher compared to those of normal parotid glands, and the ADC values of reactive lymphadenopathies were lower compared to both. The choline/creatine levels of subcutaneous and infiltrative parotid lesions were slightly higher than those of normal parotid glands. In conclusion, DWI and MRSI offer valuable information that may be characteristic of KD, which can highly suggest the diagnosis of KD when combined with morphological imaging.
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