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Molecular communication (MC) allows nanomachines to communicate and cooperate with each other in a fluid environment. The diffusion-based MC is popular but is easily constrained by the transmit distance due to the severe attenuation of molecule concentrations. In this letter, we present a decode-and-forward (DF) relay strategy for the reversible binding receptor in the diffusion-based MC system. The timevarying spatial distribution of the information molecules based on the reversible association and dissociation between ligand and receptor at the surface of receiver is characterized. An analytical expression for the evaluation of expected error probability is derived, and the key factors impacting on the performance are exploited. Results show that with a constant molecular budget, the proposal can improve the performance significantly, and the performance gain can be enhanced by optimizing the position of the relay node and the number of molecules assigned to the source node. Index Terms-Molecular communication (MC), decode-andforward (DF) relay, reversible binding, ligand-receptor I. INTRODUCTION D IFFUSION-BASED molecular communication (DbMC)is considered as a particularly effective and energyefficient approach of exchanging information among nanomachines [1]. Unlike the active transport and bacterium-based communication, DbMC is a short-to-medium range molecular communication (MC) without external energy and infrastructure. Information molecules are encoded by transmitter propagation to the receiver based on free diffusion in DbMC [2]. During the propagation, however, the attenuation of molecular concentration worsens with the increasing distance. Thus, the reliable communication is challenging for the scenario of long transmit distance.To solve this challenge, one potential solution inherited from the traditional wireless communication is to deploy relay between the transmitter and receiver. There have been several research efforts toward relay-assisted MC [3]-[6]. The design and analysis of repeaters using bacterial has been investigated in [3], an information delivery energy model for MC via bacteria relays is established. In [4] and [5], the authors propose a fixed-gain and variable-gain amplify-and-forward (AF) relay strategies. In [6], a decode-and-forward (DF) relay

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Molecular communication (MC) is a kind of communication technology based on biochemical molecules for internet of bio-nano things, in which the biochemical molecule is used as the information carrier for the interconnection of nano-devices. In this paper, the basic principle of diffusion based MC and the corresponding key technologies are comprehensively surveyed. In particular, the stateof-the-art achievements relative to the diffusion based MC are discussed and compared, including the system model, the system performance analysis with key influencing factors, the information coding and modulation techniques. Meanwhile, the multi-hop nano-network based on the diffusion MC is presented as well. Additionally, given the extensiveness of the research area, open issues and challenges are presented to spur future investigations, in which the involvement of channel model, information theory, self-organizing nano-network, and biochemical applications are put forward.

In order to achieve underwater wireless dynamic optical communication, a laser communication system is proposed based on Pulse Position Modulation (PPM). In order to achieve underwater laser communication accurately, the mathematical model of underwater laser communication was constructed with small angle analysis. The pulse position modulation demodulation algorithm is designed, and the workflow of modulation and demodulation is given in the transmit module and the receive module. In the experiment, Lumileds-470 nm light source was selected for data communication for testing at a communication rate of 15 Mbp/s. In the servo control process, the square wave signal used for stepping motor drive had a stable amplitude output and a stable time width. It can well simulate the testing process of underwater dynamic scanning. In the experiment, laser light spots were obtained under different attenuation states, and the characteristics of the light spot distribution were analyzed. The numerical reconstruction of the light spot energy was completed in MATLAB. Three types of light attenuators, 1.0%, 0.1%, and 0.01%, were used to simulate different light attenuations underwater. The test results show that the system error rate is better than 10−6 when attenuation chip is 1.0%. When attenuation chip is 0.1%, the error rate of the system is reduced to 10−4. When attenuation chip is 0.01%, a valid signal cannot be obtained by the system. The feasibility of the system is verified.