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The degeneration mechanism of viscoelastic food material in specific processing mode affects the formulation of food material processing technology. On the other hand, it determines the taste of food in the chewing process. The viscoelastic food material was taken as the research object, and experimental data were obtained through stress relaxation experiments and strain relaxation experiments of texture analyzer material. Based on Maxwell model and Kelvin model, describing small deformation of the nonlinear viscoelastic constitutive model, building a composite model was proposed. By making analysis and comparison between constructed composite model and Maxwell model and Kelvin model, it was verified that the constructed composite model can be better described as the mechanical behavior of viscoelastic food material under the mode of compressed chewing, which is also providing a more precise theoretical model for the processing and development of viscoelastic food material.

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Background Mitochondrial disease (MD) is genetically a heterogeneous group of disorders with impairment in respiratory chain complexes or pathways associated with the mitochondrial function. Nowadays, it is still a challenge for the genetic screening of MD due to heteroplasmy of mitochondrial genome and the complex model of inheritance. This study was designed to investigate the feasibility of whole exome sequencing (WES)‐based testing as an alternative option for the diagnosis of MD. Methods A Chinese Han cohort of 48 patients with suspect MD features was tested using nanoWES, which was a self‐designed WES technique that covered the complete mtDNA genome and 21,019 nuclear genes. Fourteen patients were identified with a single genetic variant and three with single deletion in mtDNA. Results The heteroplasmy levels of variants in mitochondrial genome range from 11% to 100%. NanoWES failed to identify multiple deletions in mtDNA compared with long range PCR and massively parallel sequencing (LR‐PCR/MPS). However, our testing showed obvious advantages in identifying variations in nuclear DNA. Based on nanoWES, we identified two patients with nuclear DNA variation. One of them showed Xp22.33‐q28 duplication, which indicated a possibility of Klinefelter syndrome. Conclusion NanoWES yielded a diagnostic rate of 35.4% for MD. With the rapid advances of next generation sequencing technique and decrease in cost, we recommend the usage of nanoWES as a first‐line method in clinical diagnosis.

Objective: To observe the clinical effect of catheter-directed thrombolysis on deep venous thrombosis (DVT) of lower extremity after burn.

With the development of green agriculture, the demand of farmers for operation loans is increasing. Supply chain finance is becoming a new way to solve the problem of difficult credit in agricultural development. As the importance of sustainability issues continues to rise, there are growing numbers of practical examples of combining agricultural supply chain finance (ASCF) with sustainability, and the attendant risks are emerging. The objectives of this study are first to construct a risk indicator system for sustainable ASCF, then to propose a fuzzy decision method that considers the confidence of decision-makers, and finally to perform a risk assessment of a credit case in the coffee bean supply chain. A combination of the neutrosophic enhanced best–worst method (NE-BWM) and combined compromise solution (COCOSO) is used to evaluate risk problems. The practicality and effectiveness of this research method is verified by a numerical simulation and a comparison with the method. The results show that the credit rating of core companies is the most important indicator. In the context of green and sustainable development, this indicator system is more suitable for the current green transformation development of agriculture and can help decision-makers scientifically and reasonably assess the risk level of ASCF. When loans are needed to transform green agriculture, this study provides new ideas for credit models for various actors in the agricultural supply chain and offers a new entry point to the issue of sustainable agricultural development.