In recent years, application of recommendation algorithm in real life such as Amazon, Taobao is getting universal, but it is not perfect yet. A few problems need to be solved such as sparse data and low recommended accuracy. Collaborative filtering is a mature algorithm in the recommended systems, but there are still some problems. In this paper, a novel collaborative filtering recommendation algorithm based on user correlation and evolutionary clustering is presented. Firstly, score matrix is pre-processed with normalization and dimension reduction, to obtain denser score data. Based on these processed data, clustering principle is generated and dynamic evolutionary clustering is implemented. Secondly, the search for the nearest neighbors with highest similar interest is considered. A measurement about the relationship between users is proposed, called user correlation, which applies the satisfaction of users and the potential information. In each user group, user correlation is applied to choose the nearest neighbors to predict ratings. The proposed method is evaluated using the Movielens dataset. Diversity experimental results demonstrate that the proposed method has outstanding performance in predicted accuracy and recommended precision.
Apolipoproteins (APOs), the primary protein moiety of lipoproteins, are known for their crucial role in lipid traffic and metabolism. Despite extensive exploration of APOs in cardiovascular diseases, their roles in cancers did not attract enough attention. Recently, research focusing on the roles of APOs in cancers has flourished. Multiple studies demonstrate the interaction of APOs with classical pathways of tumorigenesis. Besides, the dysregulation of APOs may indicate cancer occurrence and progression, thus serving as potential biomarkers for cancer patients. Herein, we summarize the mechanisms of APOs involved in the development of various cancers, their applications as cancer biomarkers and their genetic polymorphism associated with cancer risk. Additionally, we also discuss the potential anti-cancer therapies by virtue of APOs. The comprehensive review of APOs in cancers may advance the understanding of the roles of APOs in cancers and their potential mechanisms. We hope that it will provide novel clues and new therapeutic strategies for cancers.
Community detection in signed networks has been studied widely in recent years. In this paper, a discrete difference equation is proposed to imitate the consistently changing phases of the nodes. During the interaction, each node will update its phase based on the difference equation. Each node has many different nodes connected with it, and these neighbors have different influences on it. The similarity between two nodes is applied to describe the influences between them. Nodes with high positive similarities will get together and nodes with negative similarities will be far away from each other. Communities are detected ultimately when the phases of the nodes are stable. Experiments on real world and synthetic signed networks show the efficiency of detection performance. Moreover, the presented method gains better detection performance than two existing good algorithms.
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