Electrospinning technology is considered to be one of the efficient, convenient, and low-cost technologies for preparing nanofibers, which can be applied in various industries, including filtration, catalysis, and energy. Here, aiming at the performance requirements of the nanometer fiber filter membrane for filtering PM2.5, the preparation of the nanofiber filter membrane was realized based on multi-needle electrospinning equipment. Meanwhile, by adding silver nitrate to the spinning solution, a polyvinylidene fluoride antibacterial nanofiber filter layer with high filtration efficiency and low resistance was successfully prepared on the traditional air conditioning filter meshes. We found that four key factors affecting the filtration performance include ambient humidity, substrate meshes, voltage, and production rate. Among them, voltage and production rate are the key factors affecting the filtration performance. According to the development trend of multifunctional nanofiber membranes, the preparation of air conditioning filters with nanofibers as the main filter material was realized, producing air conditioning filter membranes with antibacterial and deodorizing functions. This article provides a reliable experimental basis and empirical reference for the preparation of nanofiber membranes based on multi-needle electrospinning technology.
Many strategies have been adopted to engineer bone-ligament interface, which is of great value to both the tissue regeneration and the mechanism understanding underlying interface regeneration. However, how to recapitulate the complexity and heterogeneity of the native bone-ligament interface including the structural, cellular and mechanical gradients is still challenging. In this work, a bioinspired grid-crimp micropattern fabricated by melt electrospinning writing (MEW) was proposed to mimic the native structure of bone-ligament interface. The printing strategy of crimped fiber micropattern was developed and the processing parameters were optimized, which were used to mimic the crimp structure of the collagen fibrils in ligament. The guidance effect of the crimp angle and fiber spacing on the orientation of fibroblasts was studied, and both of them showed different levels of cell alignment effect.. MEW grid micropatterns with different fiber spacings were fabricated as bone region. Both the alkaling phosphatase activity and calcium mineralization results demonstrated the higher osteoinductive ability of the MEW grid structures, especially for that with smaller fiber spacing. The combined grid-crimp micropatterns were applied for the co-culture of fibroblasts and osteoblasts. The results showed that more cells were observed to migrate into the in-between interface region for the pattern with smaller fiber spacing, suggested the faster migration speed of cells. Finally, a cylindrical triphasic scaffold was successfully generated by rolling the grid-crimp micropatterns up, showing both structural and mechanical similarity to the native bone-ligament interface. In summary, the proposed strategy is reliable to fabricate grid-crimp triphasic micropatterns with controllable structural parameters to mimic the native bone-to-ligament structure, and the generated 3D scaffold shows great potential for the further bone-ligament interface tissue engineering.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.