Mesenchymal cell movement is normally constrained; however, fibronectin can provide a pathway for stromal cell migration during embryogenesis, morphogenesis, and wound healing. Cells can adhere to fibronectin via integrin and nonintegrin receptors, which bind multiple unique peptide sequences. Synthetic peptides and recombinant proteins were used to delineate the functional domains needed for human fibroblast migration over fibronectin. The 9th and 10th fibronectin type III repeats, which contain RGD and PHSRN synergy cell attachment sequences, support almost maximal fibroblast attachment, but not migration of primary dermal fibroblasts. Specific sequences within the heparin domain and the IIICS region are also required for migration. These findings predict and additional data confirm the necessity for the cooperation of multiple integrin and nonintegrin receptors for fibroblast migration on fibronectin. Such stringency of migration most likely imposes an immense constraint on normal mesenchymal cell mobility in unperturbed tissue. Loss of such restraint may be critical for the migration cancer cells through the extracellular matrix.
With the gradual deepening of electricity market reform, electric power industry has not completely in accordance with the annual consolidated planning to organize the operation and development, but more and more by the macro-economic environment, the coal market fluctuations and other factors. This requires that power enterprise groups in the process of planning and controlling market boundaries to assess the scheme under various boundary conditions of the market. Presented a comprehensive plan of electric power Enterprise assessment method, according to the changing market environment, an amendment to the selected indicators, adjust the index value, so as to better meet corporate management target.
Cost-effectiveness analysis model is established in this paper to examine the influence of the incorporation of wind power to the whole power supply system. Thermal power plants are used as the backup for wind power due to its intermittence, which will increase the coal consumption so that lower the profit of the thermal power plants. A further optimization model is also established to work out the profit of both the power plants and the grid after the incorporation of wind power, and the influence on the CO2 emission as well. It came to the conclusion that although the cost of coal-fired power plants increases because of offering back up to the wind power, CO2 emission from the generation side will decline which has the environmental benefit.
The development of new energy materials offers a solid foundation for the expansion of renewable and other clean energy such as onshore/offshore wind energy, solar energy, biomass and nuclear energy. With the rapid growth of the installed capacity of these clean energy types, it is urgent to further improve the generation dispatch mode to guarantee the grid connection. An energy-saving generation dispatch model is established to find out the optimal unit commitment of thermal power and other clean power, with a consideration of carbon emission limitation.
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