The aim of this study is to describe a case of dentigerous cysts of a young patient successfully treated as well as clinical and radiographic follow-up. A 10-year-old female patient was referred to the Buccomaxillofacial Surgery and Traumatology Service of the Regional University Hospital of Campos Gerais. The patient's panoramic radiograph revealed a well-defined radiolucent unilocular area associated to the crown of the second permanent right lower molar, which was impacted. In addition, the permanent upper canines were enclosed, suggesting a dentigerous cyst. A conservative treatment was determined, through marsupialization of the lesions. The histopathology examination confirmed the clinical diagnosis of dentigerous cysts. Longitudinal clinical and radiographic monitoring was essential to certify the regression of the lesion, as well as bone neoformation, thus promoting the eruption and maintenance of the affected permanent teeth.
Background
Several drugs are capable of promoting changes in bone metabolism. The aim of this study was to evaluate the effect of long-term low-dose aspirin (LDA) therapy on implant osseointegration.
Methods
Male Wistar rats were divided into 4 groups (n = 8/group) according to oral gavage solution received prior (42 days) to the implant surgery on the tibia. The control group was treated with saline solution for 7 (CG-7) and 28 (CG-28) days. The use of low-dose aspirin was performed in AG groups (6.75 mg/kg of aspirin) for 7 (AG-7) and 28 (AG-28) days. After experimental periods, histomorphometric evaluation of bone-to-implant contact (BIC) and the bone area between threads (BABT) was performed.
Results
Reduced BIC values were detected in AG-7 (62.8% ± 17.1) group compared to AG-28 (91.9% ± 5.4), CG-7 (82.7% ± 15.2), and CG-28 (89.9% ± 9.7). BABT evaluation revealed lower values in AG-7 (70.9% ± 15.2) compared to AG-28 (95.4% ± 3.7) and CG-28 (87.1% ± 10.2) groups.
Conclusions
The treatment with low doses of aspirin promoted a discrete inhibitory effect in the early stages (7 days) of repair after implant placement, specifically in the bone deposition. However, these effects were not detected in the late stages (28 days), considering BIC and BABT parameters.
This case report showed an AOT in a 12-year-old female patient referred for orthodontic-surgical of both impacted right mandibular canine and lateral incisor. Cone beam computed tomography revealed a well-defined mixed hyperdense/hypodense lesion, involving the crown of the mandibular lateral incisor. The surgery consisted in surgical exposure of the mandibular right canine and lateral incisor, bonding of the lateral incisor for orthodontic traction and curettage of the mandibular lesion. Histopathological examination revealed several columnar epithelial cells with minimal stromal connective tissue, lobular pattern and rosettes and duct-like structures, confirming the diagnosis of AOT. After, the patient was referred for orthodontic traction of the impacted teeth. At 1 and 3-year postoperatively, follow-ups examinations showed extensive bone repair, resolution of the tooth-retention and absence of recurrence. Although AOT is an uncommon lesion in the mandible, it should be considered in the differential diagnosis of the mixed profile lesions in this region.
Milhões de exodontias são realizadas todos os anos. A analgesia pré-emptiva (APE) com dexametasona (DEX) é eficaz para reduzir algumas complicações deste procedimento. É bastante frequente o atendimento odontológico de pacientes que utilizam baixas doses de Aspirina (BDAAS). Avaliou-se a segurança da APE com DEX nas exodontias em ratos submetidos ao uso crônico de BDAAS. Os animais foram divididos em 4 grupos (Controle, DEX, AAS e AAS+DEX) replicados em dois experimentos (E1sacrifício 2 dias após a exodontia; e E2 -sacrifício 28 dias após a exodontia), totalizando 8 grupos experimentais, recebendo uso crônico de BDAAS e dose única de DEX, via gavagem. Foram coletados e analisados os estômagos e as hemimandíbulas. As avaliações gástricas demonstraram que houve aumento das lesões nos grupos AAS e AAS+DEX em relação ao Controle e ao grupo DEX (p<0,05). Não houve diferenças significativas entre o grupo DEX e o grupo Controle, nem entre o grupo AAS e AAS+DEX (p>0,05). Nenhum animal apresentou infecção e não houve diferença significativa no reparo ósseo alveolar (ROA) (p>0,05). Nossos resultados corroboram estudos mostrando que BDAAS aumentam os riscos de lesões gástricas, não sendo potencializados por dose única de DEX, além disso, os resultados de nossa pesquisa sugerem que esta associação de DEX em dose única com BDAAS não aumenta o risco de infecções e não interfere no ROA 28 dias após a exodontia. Em nosso trabalho concluímos que a DEX foi segura para o uso como analgesia pré-emptiva na exodontia em ratos tratados cronicamente com baixas doses de aspirina.
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