Objective: To evaluate the effects of a coexisting epiglottic cyst on the clinical course and airway management of acute epiglottitis in adults. A review of the airway risk factors were studied in adults with acute epiglottitis in South Korea from 1997 to 2009. Design: Retrospective chart review. Setting: Academic tertiary care referral medical center. Participants: The study included 117 adult patients that were diagnosed with acute epiglottitis laryngoscopically over a period of 12 years. Two distinct groups were identified: one with acute epiglottitis associated with an infected epiglottic cyst (n = 29, 25%) and the other with acute epiglotittis without a cyst (n = 88, 75%). Main outcome measures: Patient background data, clinical manifestations, laboratory data, airway management, outcomes, and recurrence were recorded. Results: Eight (28%) out of 29 patients with an infected epiglottic cyst required airway intervention compared to the four (5%) out of 88 patients without a cyst. The difference between the two groups was statistically significant (P = 0.001). Five out of six patients with recurrent acute epiglottitis had a coexisting epiglottic cyst. The recurrence of acute epiglottitis in patients with a cyst was significantly more frequent (P = 0.003). Twelve patients (10%) required airway intervention. There was no mortality found in this study. Logistic regression analysis showed that an older age, dyspnoea, a high pulse rate, and the presence of an epiglottic cyst were associated with an increased risk for airway obstruction. Conclusions: The results of this study showed that a pre-existing epiglottic cyst might be associated with a suppurative infection of the supraglottis. Infected epiglottic cysts increased the risk for airway obstruction and recurrence of acute epiglottitis.
Background : In situation of insufficient alveolar bone, guided bone regeneration (GBR) or bone grafting is performed. The long-term success rate for this will need to be evaluated for the life of the implant. Aim/Hypothesis : The purpose of this study was to determine the long-term survival and success rate after implant placement with guided bone regeneration (GBR) or bone grafting and to find the factors related with GBR that can affect the success rates of implants. Materials and Methods : A total of 162 implants of 70 patients accompanied by GBR or bone grafting in the department of periodontology, Chonnam National University Dental Hospital from December 2008 to 2013 were enrolled. The survival rate of the implants and the success rate which classified by the ICOI were calculated by measuring the loss of the alveolar bone around the implant through standard intraoral radiographs. To investigate the correlation between the success rate and the factors related with GBR that can affect the success rate of implants, chi-square test and binominal logistic regression analysis were conducted. Results : Up to 8 years follow-up, 13 out of 162 implants failed, resulting in 92.0% survival. Of the 149 implants, 126 implant showed less than 2 mm of marginal bone loss, showing a success rate of 77.8%. Bone resorption amounts around implants was-0.90 ± 1.51 mm (-3.93 to 1.61 mm) in less than 3-year follow up (N = 15), 0.14 ± 1.54 mm (-5.33 to 6.76 mm) in 3-7 year follow up (N = 107) and 0.57 ± 1.43 mm (-3.23 to 3.03 mm) over 7 year follow-up (N = 27). It was observed that the bone resorption was increased and the success rate decreased over time. The chi-square analysis showed significance for the implant site (P = 0.003). In binominal logistic regression analysis, the success rate of implants placed in the maxillary posterior region (P = 0.004) was significantly lower. In addition, there were no significant differences according to gender, age, type of connection, smoking, diabetes, SPT, the severity of periodontitis, type of bone graft materials, and type of membranes. Conclusions and Clinical Implications : Within our results, up to 8 years follow-up, the success rate was 77.8%, the success rate of implants with GBR or bone grafting in the maxillary posterior region was low.
Tooth autotransplantation refers to tooth transplantation from the donor to the recipient site of the same individual. Occasionally, there are situations where autotransplantation cannot be carried out immediately at clinic. In such cases, donor teeth cryopreservation is necessary to overcome limited indications. Cryopreservation media and nutrients play essential roles in preserving the periodontal ligament cells' activity. Several studies have focused on cryopreservation media and nutrients. Platelet-rich plasma (PRP) contains lots of growth factors without inducing immunologic responses or pathologic complications. Therefore, self serum and PRP might be positive factors in the cryopreservation process for preserving the periodontal ligaments (PDLs) viability. In this study, beagle dog's incisors were cryopreserved for three months in different cryopreservation media, including Dulbecco's modified eagle medium (DMEM, containing DMSO), DMEM+20% self serum, DMEM+20% self serum+PRP, and DMEM+20% fetal bovine serum (FBS). Histological results revealed that DMEM+20% self serum+PRP and DMEM+20% FBS groups showed significantly less root resorption and higher regeneration of periodontal ligament cells and that PRP is a positive factor in the cryopreservation process to preserve PDLs viability. Therefore, cryopreservation media with PRP will be a good periodontal tissue regeneration option after long-term cryopreservation in a tooth autotransplantation procedure.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.