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There was a statistically significant decrease in the mean total area and number of lesions between the time of disease activity and disease quiescence (P < 0.01). Our results suggest that indocyanine green angiography has a role not only in diagnosis but also in monitoring treatment effectiveness; lesions can be reversible with treatment and their reappearance may be an indicator of disease relapse.

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The majority (67.25%) of our patients enjoyed a good visual outcome (most recent visit best-corrected visual acuity equal to or better than 20/40 and within one line or better from the baseline) with immunomodulatory therapy. We found that cystoid macular edema, macular ischemia, and lower best-corrected visual acuity during the first consultation visit were significant independent risk factors for poor visual outcome.

Animal genetic resources are critical to livestock productivity and adaptability, facilitate resilience to climate change, and are a key contributor to food security and livelihoods around the world. The Global Plan of Action for Animal Genetic Resources (Global Plan), consisting of four Strategic Priority Areas (SPAs: Characterization; Sustainable use; Conservation; Policy), provides a framework to guide countries and other stakeholders on actions to improve the management of animal genetic resources. Assessing, reporting and monitoring the progress and implementation of the Global Plan are critical processes for understanding global commitments made to enhance livestock genetic diversity. In this study, three rounds of reporting (2012, 2014, and 2019) from Member Nations of the Food and Agriculture Organization of the United Nations were quantitatively analyzed to gain insight into the progress and implementation of the Global Plan by grouping questionnaires responses into quantitative indicator scores. Variations were found in indicator scores across SPAs, year, and regions, as well as within regions. Countries from North America and Europe and the Caucasus reported higher scores, while most BRICs countries (Brazil, India, China, South Africa) had high implementation scores relative to other countries in the same region. A significant positive correlation was observed between mean implementation scores in 2019 and GDP per capita (r = 0.456). Countries reporting higher implementation of in situ conservation also indicated higher proportions of breeds at risk. Significant progress was reported over the years for three of the four SPAs; SPA3 (conservation) was not found to have significantly improved. Despite the gains that have been made since 2012 in management of animal genetic resources, much remains to be done. The population status of nearly 60% of breeds is unknown while almost three quarters of breeds of known status are at risk of extinction. Efforts must continue to improve management of livestock genetic diversity, with further investments and development of approaches that support socio-economic viability of local genetic resources.