Patients with a high total nevus count (TNC) merit a total-body examination, but a simple strategy to identify these high-risk individuals is essentially missing. The aim of this study was to investigate the correlation between the number of melanocytic nevi on both arms and the TNC, and to evaluate patient variables that may have an effect on this association. In this multicenter, cross-sectional study, 2175 patients were examined and the mean number of arm nevi in relation to TNC was calculated. A mean value of fewer than 10 arm nevi was found in patients with TNC lower than 51 and a mean value of greater than 19 arm nevi was scored in patients with TNC greater than 50. These values remained unchanged after adjustment for various patient variables. In relation to TNC greater than 50, the presence of 20 or more arm nevi had specificity and negative predictive values of 95.2 and 89.6%, respectively. The sensitivity was 65.5% in patients younger than 50 years of age and 37.5% in the older age group. The number of arm nevi was significantly higher in individuals with a history of melanoma and in those with a melanoma detected during the study period. The presence of 20 or more nevi on the arms is an independent predictor of a high TNC and risk of melanoma. This sign thus represents a simple and rapid screening tool for either the primary care physician or the dermatologist to help identify high-risk patients.
C. trachomatis was predominant bacterial species found in urethra in men with nongonococcal urthretitis. Mixed infections were frequent.
Strawberries (Fragaria × ananassa) in Montenegro have become an increasingly important economic crop in recent years. During May 2011, severe fruit damage in strawberry cv. Clery was observed in two fields in the Podgorica region. Fruit symptoms were typical for strawberry anthracnose: sunken, dark brown to black circular lesions appeared on maturing fruits. However, no stem, crown, or foliar symptoms were observed. Under wet conditions, orange masses of conidia were produced in acervuli in the center of lesions. Conidia were hyaline, aseptate, cylindrical, with pointed ends, measuring 9.8 to 17.2 (mean 14.3) × 2.5 to 6.1 (mean 4.4) μm. Colonies on potato dextrose agar (PDA) were initially white, then turned gray as conidia formed in orange to salmon pink masses around the center of the culture. Setae or an ascigerous stage were never observed in culture or on the host. Koch's postulates were fulfilled by inoculating ripe and unripe asymptomatic fruits (20 of each, removed from strawberry plants cv. Clery) with the isolated fungus. Fruits were sprayinoculated (106 conidia/ml). An equal number of noninoculated fruits were used as a control. After incubation time of 2 to 3 days at 25°C in a moist chamber, symptoms appeared on inoculated ripe fruits. On unripe fruits, the lesions developed only 3 to 4 days after the inoculation. No symptoms were found on control fruits. The fungus was reisolated from fruits, after which typical morphological characteristics developed in culture as described above. On the basis of the symptoms, the morphological and cultural characteristics of the fungus, and the pathogenicity test, the disease was identified as strawberry anthracnose caused by Colletotrichum acutatum, which is in accordance with previous reports (1,2,3,4). The isolate was submitted to the Centraalbureau voor Schimmelcultures in the Netherlands (CBS 131813). The internal transcribed spacer (ITS) region of the fungal DNA was amplified with ITS1F and ITS4 primers, sequenced, and submitted to NCBI GenBank (Accession No. JQ424934). BLASTn searches of GenBank using the ITS sequence revealed 99% similarity with database sequences of C. acutatum. Since the pathogen was found in the main Montenegrin strawberry production area, it poses a threat to strawberry production in Montenegro. To our knowledge, this is the first report of anthracnose fruit rot of strawberry in Montenegro. References: (1) S. G. Bobev et al. Plant Dis. 86:1178, 2002. (2) F. M. Dai et al. Plant Dis. 90:1460, 2006. (3) U. Nilsson et al. Plant Dis. 89:1242, 2005. (4) A. Stensvand et al. Plant Dis. 85:558, 2001.
Trois phytophthoroses des cultures dans la région méditerranéenne du Monténégro sont présentées: la gommose des agrumes, maladie connue depuis longtemps, mais dont l'importance est devenue négligeable grâce à la pratique du greffage; Phytophthora capsici sur poivron, constaté pour la première fois dans le Monténégro il y a une dizaine d'années, et Phytophthora nicotianae var. nicotianae, provoquant le pied noir du tabac, connu en Yougloslavie seulement depuis 1983. Les phytophthoroses du poivron et du tabac restent toujours des maladies potentiellement importantes dues à la nécessité d'irrigation de ces cultures et á la difficulté d'une lutte chimique rationnelle.
The examination included 50 patients with chronic plaque-type psoriasis to whom 0.25% desoximetasone and dithranol was applied on the psoriatic lesions in the period of 21 days. The changes were measured before and every 7 days after the beginning of therapy by the combined application of A- and B-mode echosonography. RESULTS. At the beginning of the examination, the average values of the enter echo were 0.67 +/- 0.53 mm; hypoehogen shadow 0.30 +/- 0.11 mm, and dermis thickness 3.03 +/- 1.05 mm. On the first check up, the average values of the enter echo were 0.45 +/- 0.29 mm; hypoechogen shadow 0.23 +/- 0.08 mm and dermis thickness 2.65 +/- 0.97 mm. On the second check up, the average values of the enter echo were 0.30 +/- 0.18 mm; hypoechogen shadow 0.21 +/- 0.18 mm, dermis thickness 2.18 +/- 0.82 mm. On the third check up, the average values of the enter echo were 0.24 +/- 0.17 mm; hypoechogen shadow 0.18 +/- 0.17 mm, and dermis thickness 1.8 +/- 0.69 mm. DISCUSSION. The evaluation of the ultrasonographic characteristics revealed a significant reduction in the values in the course of the examination. Statistically significant differences were found before, during, and at the end of the examination by recording the ultrasound parameters of the epidermis and dermis and by following their modification. CONCLUSION. Precise determination of ultrasound parameters of epidermis and dermis and the possibility of recording their modification in a shorter or longer time interval can be used for monitoring and assessment of therapy effect of a medication.
Anaplastic large cell lymphoma is defined by a proliferation of large pleomorphic blasts and a constant expression of the CD30 molecule on all neoplastic cells, and has been clinically subdivided into a primary form and a secondary form. We are presenting a case of 14-year-old boy with reddish-livid papules on the skin of right half of trunk that were confluent in the lower end into solid plaque with diameter 20 x 15 cm, and enlarged lymph nodes in axilla and on neck. Lesioned skin biopsy, biopsy of lymph node and bone marrow showed pleomorphic cells, strongly CD30, and ALK positive. In our patient diagnosis was reached on the basis of morphological and immunohistochemical characteristics
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