Rhesus macaques are commonly used as a translational animal model in neuroimaging and neurodevelopmental research. In this report, we present longitudinal data from both structural and diffusion MRI images generated on a cohort of 34 typically developing monkeys from 2 weeks to 36 months of age. All images have been manually skull stripped and are being made freely available via an online repository for use by the research community.
Computational anatomical atlases have shown to be of immense value in neuroimaging as they provide age appropriate reference spaces alongside ancillary anatomical information for automated analysis such as subcortical structural definitions, cortical parcellations or white fiber tract regions. Standard workflows in neuroimaging necessitate such atlases to be appropriately selected for the subject population of interest. This is especially of importance in early postnatal brain development, where rapid changes in brain shape and appearance render neuroimaging workflows sensitive to the appropriate atlas choice. We present here a set of novel computation atlases for structural MRI and Diffusion Tensor Imaging as crucial resource for the analysis of MRI data from non-human primate rhesus monkey (Macaca mulatta) data in early postnatal brain development. Forty socially-housed infant macaques were scanned longitudinally at ages 2 weeks, 3, 6, and 12 months in order to create cross-sectional structural and DTI atlases via unbiased atlas building at each of these ages. Probabilistic spatial prior definitions for the major tissue classes were trained on each atlas with expert manual segmentations. In this article we present the development and use of these atlases with publicly available tools, as well as the atlases themselves, which are publicly disseminated to the scientific community.
The purpose of this essay is to argue that in Adam Smith, the right to subsistence is a natural right and that the reasons why it failed to reach the statute books are predominantly political. The concentration of political power in the hands of property owners and the various forms of economic dependency created by economic developments have generated, in Smithʼs view, a discrepancy between positive law and natural justice. It is upon this discrepancy that the difference of opinion lies with regard to the more general question of whether distributional matters are part of Smithʼs notion of justice. At the heart of Smithʼs analysis of all aspects of society stands the socially conditioned individual agent. The effi ciency of natural liberty as well as its morality rests on the prudent behavior and tempered attitudes of agents. The invisible hand of The Theory of Moral Sentiments suggests that the presence of private property, or more broadly stated, that of wealth inequality, does not necessarily deprive anyone of lifeʼs
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