BackgroundCalcified amorphous tumor (CAT) of the heart is a rare non-neoplastic intracavitary cardiac mass. Several case reports have been published but large series are lacking.ObjectiveTo determine clinical features, current management and outcomes of this rare disease.DesignA systematic review of all articles reporting cases of CAT in order to perform a pooled analysis of its clinical features, management and outcomes.Data sourcesAn electronic search of all English articles using PUBMED was performed. Further studies were identified by cross-referencing from relevant papers.Inclusion criteriaWe restricted inclusion to articles reporting cases of CAT in the English language literature published up to July 2014.Data extractionOne author performed data extraction using predefined data fields.ResultsA total of 27 articles, reporting 42 cases of CAT were found and included in this review.ConclusionIn this review, the most frequent presenting symptoms were dyspnea and embolic events. Mitral valve and annulus were the most frequent location of CAT. Surgery was most of the time required to confirm diagnosis, and was relatively safe. Overall outcome after surgical resection was good.

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The aim of this multicenter pilot study was to evaluate the acute safety and efficacy of the dexamethasone-eluting stent (0.5 g/mm 2 of stent) implanted in patients with de novo single-vessel disease. This study included 71 patients, 42% of whom had unstable angina pectoris. An appropriately sized BiodivYsio Matrix Lo stent loaded with a total dexamethasone dose of 0.5 g/mm 2 of stent was used. Technical device success rate was 95%. Six-month MACE occurred in two patients (3.3%). Binary restenosis rate was 13.3%.