SUMMARYPurpose: To disclose clinical, electrophysiologic, and neuroradiologic factors correlated to prognosis in patients with mesial temporal lobe epilepsy (MTLE). Methods: One hundred thirty-six MTLE patients were studied for family history, clinical characteristics, instrumental data [electroencephalography (EEG), video-EEG, neuroimaging], and outcome. The population was divided into drug-resistant (DR: 108 patients, 79.4%) and non-drug-resistant (NDR: 28 patients, 20.6%) groups; all variables were analyzed in the two groups. Results: The comparison between the two groups shows a relation between resistance to therapy and febrile seizures (FS) (DR 43.5% vs. NDR 17.8%, p = 0.008), mesial temporal sclerosis (MTS) (DR 64.8% vs. NDR 32.1%, p = 0.0025), early age at seizure onset (DR 23.1% vs. NDR 3.6% p = 0.0160), and epileptiform interictal abnormalities (DR 89.7% vs. NDR 68%, p = 0.010). FS were more frequent in patients with MTS than in patients without (46.28% vs. 26.3%, p = 0.0199). Sixty-nine patients underwent surgery and 85.3% of them had a good outcome. Conclusion: MTLE is a heterogeneous syndrome. Establishing the factors responsible for and associated with drug resistance is important for therapeutic purposes, as prompt diagnosis of drug resistance must lead to early surgical management. This study shows that FS, MTS, early age at seizure onset, and epileptiform interictal abnormalities are negative prognostic factors and that FS are related to MTS.

In labor market surveys, questions regarding respondent time allocation are typically framed with respect to activities in the past week, the past month, or the past year.Two other measures are used in developing country settings, the home status rate (HR) and the jobless rate (JR). The home status rate is the proportion of the population that is neither in the labor force nor in school. It measures the group that has left school

The aim of this study is two-fold. First, based on summary data at the country-level for an unusually large set of developing countries originally obtained from household sample surveys conducted between 1993 and 2003, we construct a detailed profile of child economic activity and child labor, attempting, wherever the data permit, to identify similarities and differences across regions and between genders. Second, we link our country-level data on child economic activity and child labor to country-level indicators of the state of economic and social development in the same time period in order to (1) ascertain if cross-country correlations previously identified in the literature are found in our data and (2) illumine other possible correlations that may exist. As part of this exercise, we examine one important relationship that has thus far not been directly investigated in the literature, namely, the cross-country correlation between child labor, agriculture and poverty.

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The aim of this study was to evaluate the prevalence of mood and eating disorders in patients with menstrual migraine. Quality of life and disability were also assessed. The study confirmed the presence of significant disability and poor quality of life due to migraine even in a selected subgroup of patients affected with menstrual migraine. In contrast with the previous literature we did not find any difference in the prevalence of mood and eating disorders.