is an indigenous medicinal herb commonly used for the treatment of gastro ulcers. In the current investigation the aerial methanolic extract of was investigated for their antiulcer activity using pylorus ligation and ethanol in experimental rats. The extract was administered at the doses of 200 and 400 mg/kg b.w. orally for 3 days. However, higher dose of the extract subsequently reduced gastric ulcer induced aberrations by pylorus ligation (70.05%) and ethanol (78.16%) as judged by their altered biochemical parameters such as free acidity, total acidity, total carbohydrate, total protein and pepsin activity. Furthermore, macroscopic examination of rat's stomach also showed that the pretreatment with methanolic extract notably lowered the pylorus ligation and ethanol induced ulcers. As perceived in the present study, evidently, our findings basically supports the potency of the methanol extracts of to treat gastrointestinal related disorders, thus lends pharmacological credence to the suggested folklore use.
Preliminary phytochemical screening and evaluation of in vitro antimicrobial activity of aerial parts of methanolic extract of the traditional medicinal herb, Cissus setosa were carried out. The results of the study report the presence of almost all major secondary metabolites except alkaloids in the extract. The strong antibacterial inhibition was noted against the gram positive bacteria, Micrococcus luteus (10 mm / 500 µg of sample) and strong antifungal inhibition was noted against the species, Candida parapsilopsis (10 mm / 1500 µg of sample).
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