Background: When evaluating a pediatric patient with abdominal pain, identification of a small-bowel to small-bowel intussusception (SBI) on radiologic imaging can create a diagnostic dilemma. The clinical significance and need for surgical exploration of SBI is highly variable, as most of them are considered clinically insignificant. We hypothesize that combination of clinical and radiologic factors in an exclusively SBI population will yield factors that guide the clinician in making operative decisions. Methods: A comprehensive database from a pediatric tertiary hospital was reviewed from 1/1/2011 to 12/31/2016 for any radiographic study mentioning intussusception. Results were reviewed for patients having only SBI (i.e. not ileo-colic intussusception) and this comprised the study cohort. The electronic medical records for these patients were reviewed for clinical presentation variables, need for operative intervention, and identification of the intussusception during surgery. Patients with SBI due to enteral feeding tubes were excluded from the study. Results: Within the study period, 139 patients were identified with a small-bowel intussusception (SBI) on radiologic imaging. Univariate analysis yielded numerous clinical and radiologic factors highly predictive for need for surgical intervention. However upon multivariate analysis, only a history of prior
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