HighlightsExtracts of less polarity from B. rubescens displayed significant antifungal activity.Two coumarins (xanthyletin and 7-demethylsuberosin) were isolated from antifungal extracts of B. rubescens.A chromatographic method to detect and quantify both coumarins is described.Xanthyletin and 7-demethylsuberosin exhibited in vivo and in vitro strong antifungal activity.7-Demethylsuberosin was metabolized slowly by C. gloeosporioides to marmesin and decursinol.
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