Juvenile xanthogranuloma (JXG) is the most frequent form of non-Langerhans cell histiocytosis. We present a case of giant congenital JXG in a 7-week-old boy, who had a firm and incompressible lesion, measuring 3 × 4 cm in diameter, on his right flank. The clinical appearance of the lesion and the ultrasound results suggested a vascular tumor, such as a hemangioma. Histology confirmed a JXG, although there was an absence of Touton cells, which are usually pathognomonic of JXG. In light of these findings, it would be important to include JXG in the differential diagnosis of congenital tumours, particularly vascular lesions.

Cutaneous larva migrans (CLM) is a zoonotic helminthiasis frequently imported to Canada by travellers to beach destinations in the tropics. The preferred treatment is oral ivermectin. We present a case of CLM acquired within the province of Quebec, a first in our provincial health records. Our case also puts forward the use of topical ivermectin as a possibly effective CLM treatment approach as our patient was successfully treated with 1 month of an ivermectin 1% cream applied locally twice daily.

Background: Eosinophilic fasciitis is a rare sclerosing syndrome with a poorly understood etiology. Objective: We report a case of eosinophilic fasciitis in a 40-year-old man undergoing treatment with natalizumab for multiple sclerosis. Natalizumab is a selective adhesion molecule inhibitor that prevents interaction of leukocytes with endothelial cells. Peripheral blood eosinophilia has been described under treatment with natalizumab, but we herein report the first case to our knowledge of eosinophilic fasciitis as a possible complication of this medication.Contexte: La fasciite à éosinophiles est un syndrome sclérosant rare, dont les causes sont mal connues. Objectif: Sera exposé ici un cas de fasciite à éosinophiles chez un homme de 40 ans, traité par le natalizumab, pour la sclérose en plaques. Le natalizumab est un inhibiteur sélectif des molécules d'adhésion, qui empêche les interactions entre les leucocytes et les cellules endothéliales. Il a déjà été fait mention d'éosinophilie sanguine périphérique en cours de traitement par le natalizumab, mais ¡I s'agit, à notre connaissance, du premier exposé de cas de fasciite à éosinophiles, décrit comme une complication possible de l'utilisation de ce médicament.

In a female patient with cyclical dermatitis, it is important to consider oestrogen or progesterone dermatitis in the differential diagnosis.

Myelodysplasia cutis is a relatively new described entity that is characterized by cutaneous plaques and nodules representing dermal infiltration of myeloid immature non-blastic cells. It can be related to myelodysplastic syndromes or myeloproliferative disorders. It has distinct clinical and histopathological features in comparison with leukemia cutis. We report an unusual case of late myelodysplasia cutis in a male patient with essential thrombocythemia. It is only the second case reported to be related to this myeloproliferative disorder.