BACKGROUND Preoperative acetaminophen and carbohydrate loading has been shown to improve the functional recovery of surgical patients. OBJECTIVE To determine the effects of preoperative acetaminophen and carbohydrates on functional outcomes and the use of pain medications after surgery in patients undergoing Mohs Micrographic Surgery (MMS) for nonmelanoma skin cancer (NMSC). MATERIALS AND METHODS One hundred patients treated with MMS for NMSC at an academic center were randomized into a control group receiving standard preoperative care or an intervention group receiving acetaminophen and carbohydrate drinks immediately before surgery. Patients rated levels of pain, thirst, hunger, anxiety, and fatigue on the day of surgery on a scale of 0 to 100, and reported through a phone interview the use of pain medications within 48 hours of surgery. RESULTS There was no significant difference between intervention and control groups in maximum pain score on the day of surgery; maximum pain score 48 hours after surgery; use of nonopioid pain medications; and use of opioids. However, the intervention group had lower anxiety levels during and at the end of surgery. CONCLUSION Patients undergoing MMS for NMSC reported very low levels of pain during and after surgery. Preoperative acetaminophen and carbohydrate loading had no impact on pain levels or the use of pain medications but did reduce levels of anxiety.
Newer scientific technological advancement in dentistry provides an array of projects such as molecular biology, cell culturing, tissue grafting, and tissue engineering. Conventional root canal treatment, apexification with biomaterials, and extractions are the procedures of choice to treat a nonvital tooth. These treatment options do not give predictable outcomes in the regeneration of the pulp tissue. This can be easily achieved by regenerative endodontics wherein the diseased or a nonvital tooth is replaced by a healthy and functional pulp-dentin complex. The rationale for regenerative endodontics follows tissue engineering techniques. This article reviews the shift in regenerative endodontic techniques.
BACKGROUND: Salivary gland swellings can result from tumors, an inflammatory process or cyst. Fine needle aspiration cytology(FNAC) is a diagnostic tool for evaluating neoplastic and non neoplastic swelling of salivary gland. The objective of this study was to evaluate the diagnostic accuracy and sensitivity and specificity of fine needle aspiration cytology in numerous salivary gland lesions and with its histopathological correlation. METHOD: The study was conducted in department of pathology; Amc met medical college, Ahmedabad, Gujarat, India, for duration of 1 year from January 2019 to January 2020. During the study period 44 cases of fine needle aspiration cytology of salivary gland lesions were performed. Formalin fixed (10%), surgically resected specimens were received and prepared for histopathological salivary gland lesion diagnosis. RESULT: During the study period 998 FNAC were undertaken of which 44 FNAC were of salivary gland swelling. Correlation of cytology from FNAC with histopathology tissue was possible in 9 cases, for which FNAC data was available. 62 % were from male and 38 % were from female patients. The age of patient ranged from 8 to 85 Years. 15 cases were benign swellings. 8 cases were malignant, 7 cases were cysts and 14 cases had an inflammatory etiology. CONCLUSION: Fine needle aspiration cytology (FNAC) is highly sensitive and specific procedure for diagnosis of salivary gland lesions. KEY WORDS: Salivary gland, Benign, Malignant, FNAC, Histopathology, Diagnostic accuracy. INTRODUCTION: The salivary gland system includes three pairs of major glands -parotid, submandibular and sublingual and many minor glands in the submucosa of oral cavity. Minor salivary glands can be found in the lips, floor of the mouth, gingival, cheek, hard and soft palate, tongue, tonsillar areas and oropharynx. (1) The lesions of salivary glands are commonly encountered clinical problems. They range from non neoplastic lesions to benign and malignant tumors. (2) FNAC has been widely used as a diagnostic tool for the management of various head and neck lesions. (3) It is minimally invasive, easy to perform technique. The smear evaluation is immediate and the procedure can be repeated many times to obtain more tissue for diagnosis or special investigations. (4,5) Among the primary epithelial tumors, 36% occurs in parotid glands,54% occurs in submandibular glands,09 % occurs in the sublingual gland and less than 1% occur in minor salivary gland. (6) A review of the recent reported series found that the diagnostic sensitivity of FNAC varied from 81-100% that the specificity varied from 94-100% IJABMS
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