No abstract

Aims/Objective: Urinary bladder cancer is the 7 th most common cancer seen worldwide, and is considerably more common in males than females worldwide. The present study was done to determine the age, sex incidence of the tumour occurrence and to study histopathological features of urinary bladder carcinoma with clinical background and to analyse the data descriptively. Materials and Methods: This prospective study was done with the biopsy and resected specimen of the urinary bladder carcinoma during a period of two years (October 2012-June 2014) from Yenepoya Medical College hospital, Mangalore. The specimens were received in 10% formalin and subjected to macroscopic description and appropriate relevant clinical details were noted. Standard tissue sections were given. Microscopic features were studied with H&E stained tissue sections using the parameters described in the proforma. Results: The present study was done on 43 cases of urinary bladder carcinomas. Cases occurred in age range of 42-91 years, peak incidence was seen in 6th decade of life, with a male to female ration of 3.1:1.No case was seen below 40 years of age. Haematuria was the most common presenting symptom, while lateral wall of urinary bladder was the commonest site of urinary bladder carcinoma with 58% of cases. Transitional cell carcinomas were the most common histological type found. 23 cases of non-invasive papillary urothelial carcinomas and 20 cases of invasive urothelial carcinomas were seen. Among non-invasive papillary urothelial carcinoma 15 cases were of low grade non-invasive carcinoma and 8 cases were of high grade non-invasive carcinoma. Conclusion: Urinary bladder carcinoma patients present in advanced stages with an overall poor survival. Incidence and prognosis can be improved by reduction of risk factors and early detection. Few of the most promising patient approaches for improving patient prognosis focus on techniques that allow early diagnosis in their early stages.