Index case smoking increases the risk of LTBI and should be systematically investigated. A reduction in smoking could lower the risk of infection substantially.
Antituberculosis drugs are associated with a significant number of AR that can cause significant morbidity, prolonged hospital stay and even death. Our results show that alcoholism and levels of CD4 < 350 cells/mm(3) were significantly associated with a high risk of AR and hepatitis B and C and levels of CD4 < 350 cells/mm3 were also significantly associated with hepatotoxicity.
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