ROM the time of their earliest description in the late 18th century, ~ meningiomas have been considered indolent relatively benign tumors which, when their location is favorable, can be completely removed. Yet Simpson 2~ reported recurrences in ~1~ of ~65 surgical cases; half of these were in patients in whom radical removal had been considered complete. He emphasized the invasive properties of these tumors, including limited infiltration of the brain in 4% of his cases, and alluded to two examples of definite malignancy. This propensity for vigorous activity which may progress to frank malignancy was recognized as long ago as 18582 In 19~7, Craig 6 reviewed 56 cases of intracranial meningiomas, and found 11 malignant variants. Cushing and Eisenhardt described six examples in their series of 313 meningiomas. 7 Turner, et al., 26 in a study of 370 intracranial meningeal tumors, found 36 with malignant characteristics. Moreover, extracranial nletastases of meningiomas may occur. 2'7'I0'11'13'14'16'17'21-23'25 ~nteresting]y enough, in some of these cases the microscopic appearance of both the primary and metastatic tumors was that of a benign meningioma? '11'~5'26 Still another malignant variant of the same fundamental pathological process is the diffuse, generalized, meningeal meningiomatosis. 4'5' s,~s,27 Our report concerns the solitary intracranial meningioma which, because of its microscopic appearance taken in conjunction with its gross characteristics and behavior, is deemed to be malignant. Clinical Material A review of 37 cases of intracranial meningiomas from The Mason Clinic has disclosed six patients in whom a diagnosis of malignant meningionla was made. Two of
A survey of the English literature concerning primary tumors of the liver has failed to discover a 5‐year survivor with cholangiocarcinoma. A 67‐year‐old Caucasian housewife is presented as a 7‐year cure following left lateral hepatic lobectomy. The tumor was a fortuitous finding during elective cholecystectomy and resection was accomplished at that time. The subject of hepatocarcinoma and cholangicarcinoma is reviewed, along with the history and techniques of hepatic resection. Apparently, cholangiocarcinoma has a hopeless prognosis unless found at a very early stage, as in the case presented.
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