Vidyabharati college of Pharmacy,Amravati, India. Corresponding author*: vivekp62@gmail.comThis article is available online at www.ssjournals.com ABSTRACTIn recent times, focus on plant research has increased all over the world. Acorus calamus is an important medicinal herb that is widely used. B asarone primary constituents Acorus calamus are manly believed to be responsible for its wide therapeutic actions. (Acorus calamus L., Araceae) is an aromatic herb, indigenous to Central Asia and Eastern Europe. The fragrant oils obtained by alcoholic extraction of the rhizome are mainly used in the pharmaceutical and oenological industries. Different parts of the plant showed the presence of large number of phenyl propanoids, sesquiterpenes and monoterpenes as well as xanthone glycosides, flavones, lignin lignans, steroids and inorganic constituents Alcoholic extracts of the triploid A. calamus were characterized by a higher percentage of b-asarone (11%), which was the main compound, followed by higher percentages of camphene (2.27%), E-bocimene (3.28%), camphor (1.54%), calarene (1.42%), a-selinene(5.02%) and s-cadinol (2.00%), when compared to the diploid A. calamus. The latter had higher percentages of isoshyobunone(8.62%), b-sesquiphellandrene (3.28%), preiso calamendiol (22.81%) and acorone (26.33%), and completely lacked of b-asarone. It is also reported to possess insecticidal, lucicidal, anti-inflamatory, antibacterial, antiulcer radioprotective, antispasmodic, bronchodilatory, glucosidase inhibitory, insulin sensitizing, antiepileptic, anticholinestrase, larvicidal, antibacterial, mutagenic, anticonvulsant, neuroleptic, smooth muscle relaxant and smooth muscle stimulant activity.
Since 5000 BC, medicinal plants have been used in India as part of the Ayurvedic medical system. Medical professionals frequently use herbal remedies. Taraxacum officinale, commonly called dandelion, is a perennial plant belonging to the family Asteraceae. It is also known as wet-a-bed, lion’s tooth, priest’s crown, blowball, milk gowan, wild endive, white endive, puffball, and Irish daisy. Long and upright flowering stalks with a single terminal inflorescence are present. It has numerous medicinal properties due to phytochemicals found in the plant's flower, leaf, stem, and roots. Sesquiterpenes found in dandelion root extracts. The root also includes a number of phenolic substances. The two sesquiterpenes taraxinic acid b-Dglucopyranoside and 11, 13-dihydrotaraxinic acid b-Dglucopyranoside An extract of combined dandelion leaves and flowers has been found to contain a number of flavonoid glycosides. Dandelion roots and leaves have historically been used to treat liver issues. Additionally, Native Americans used dandelion to treat heartburn, swelling, skin issues, kidney disease, and upset stomach. Research has been conducted to back up the descriptions of taraxacum that have been made so far. Up to doses of 10 g/kg (per oral) and 4 g/kg (intraperitoneal) of dried drug -per kilogramme body weight- in rats and mice, ethanolic extracts demonstrated very low toxicity.
The second-leading cause of cancer-related death in women is breast cancer, which is the most prevalent disease among females. The majority of breast cancers (about 70%) fall under the luminal A subtype, which is indicated by the presence of the estrogen receptor (ER +) but not by the amplified human epidermal growth factor receptor (HER2). The understanding of breast cancer has advanced with the identification of various intrinsic subtypes. This review focuses on the landscape of the luminal A subtype, its standard treatment regimen, under process clinical trial and the novel treatment regimens of luminal A breast cancer. OTUD7B oestrogen receptor stabiliser, BTG2 as a tumour target, CCAT2 in Regulating Luminal Subtype of Breast Cancer, and miRNA Expression Profiles in Luminal A Breast Cancer are some of the newer therapies for luminal A breast cancer that are discussed in this review. The ideal course of treatment for people with luminal A-subtype cancers is still unknown in the age of precision medicine. Our ability to actualize the promise of precision medicine—the correct treatment, for the right patient, at the right time—will be made possible by the development of tumour panels to examine these validated biomarkers. These unique tumour traits will become more significant in deciding the best course of treatment for each individual patient in the current era of precision medicine, where the aim is to neither overtreat nor undertreat patients. However, more thorough investigation is required in this area.
Argemone mexicana Linn belonging to family papaveraceae is widely distributed plant in tropical and sub-tropical regions of the world. The Papaveraceae, also known as the poppy family, is a family of flowering plants with 44 genera and about 760 species that is significant from an ethnopharmacological perspective. In India, It can be found alongside roads, in fields, and near bodies of water. It has roots, flowers, and leaves. It also goes by the name "Mexican Poppy." The current paper provides a review of Argemone mexicana Linn. thorough chemistry and pharmacology. This plant is one of the most important species in traditional systems of medicine. Despite the fact that alkaloids are mostly prevalent, the plant is a source of a wide variety of chemical elements. Some plant parts have hazardous consequences in addition to pharmacological efficacies. In this article, phytochemical, morphological, microscopical, and pharmacological investigations are reviewed. Current knowledge about this plant's chemistry and pharmacology may be useful for directing researchers who want to conduct additional research in these areas.
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