Poster abstracts nor functional cardiac anomalies were taken into account for this purpose. Results: A total of 57 (3.8%) cases of sCHD were found in the entire population, the incidence of sCHD was 3.25% in DC, 4.35% in MC and in TTTS cases was about 8%. 34 (59.6%) of cases underwent selective feticide because of either associated anomalies or severity of CHD. 7 (12.3%) died spontaneously in-utero and 16 were followed until birth, 75% of which was preterm (mean gestational age 29 +/− 2 weeks). 4 (25%) of cases were severe pulmonary stenosis (all of them in previous TTTS cases), two of which underwent pulmonary valvuloplasty at 4 th and 7 th day of life. 4 (25%) presented anomalous vein drainage systemic (3) and pulmonary (1). 3 (18.7%) fulfilled criteria for Fallot tetralogy. 3 (18.7%) had aortic coarctation. 2 (12.5%) presented cono-truncal anomalies (TGA and truncus). Neonatal intensive care stay was very long (mean of 74 +/− 23 days) because of prematurity and surgical interventions. Conclusions: sCHD have a higher incidence among twins, in TTTS the incidence of pulmonary stenosis is even higher than in other twins. Cardiac thorough screening is mandatory in all TP, particularly in MC.
P25.07The clinical presentation and outcome of fetal isolated ductus arteriosus aneurysms
Introduction:Although the association between abnormal middle cerebral artery (MCA) Doppler and fetal growth restriction is well established, its nature remains undefined. We sought to establish the relationship between MCA Doppler pulsatility index (PI) and abdominal circumference (AC) in babies with severe early onset fetal growth restriction. Methods: Cases with estimated fetal weight < 500 g and abnormal umbilical artery Doppler at 24 weeks were included. Serial MCA Doppler and abdominal circumference measurements were performed to delivery. These measurements were expressed as zscores and analyzed using functional linear discriminatory analysis (FLDA). The longitudinal curve was converted into a correlation coefficient expressing the relationship between the measurements. Results: 12 women were studied, comprising 51 scans. There was a positive correlation between MCA z-score and AC z-score (Spearman correlation coefficient = 0.991; p < 0.0001).
Conclusions:We describe a new technique for longitudinal analysis to demonstrate the relationship between MCA Doppler and the degree of fetal growth restriction as assessed by z-scores, rendering the data gestation independent. The smaller the AC z-score, the lower the MCA PI z-score, a finding consistent with cerebral blood flow redistribution that occurs with progressive hypoxia and growth restriction.
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