Stroke is the main cause of motor and cognitive disabilities requiring therapy in the world. Therefor it is important to develop rehabilitation technology that allows individuals who had suffered a stroke to practice intensive movement training without the expense of an always-present therapist. We have developed a low-cost vision-based system that allows stroke survivors to practice arm movement exercises at home or at the clinic, with periodic interactions with a therapist. The system integrates a virtual environment for facilitating repetitive movement training, with computer vision algorithms that track the hand of a patient, using an inexpensive camera and a personal computer. This system, called Gesture Therapy, includes a gripper with a pressure sensor to include hand and finger rehabilitation; and it tracks the head of the patient to detect and avoid trunk compensation. It has been evaluated in a controlled clinical trial at the National Institute for Neurology and Neurosurgery in Mexico City, comparing it with conventional occupational therapy. In this paper we describe the latest version of the Gesture Therapy System and summarize the results of the clinical trail.
We describe the chemical mechanical planarization (CMP) of copper damascene structures using an IC1400 pad and four different types of slurries. Two alumina-based slurries and two silica-based slurries were evaluated. After successful removal of the excess Cu, we examined the topography of the planarized structures using scanning electron microscopy. The effects of the CMP process on spacer erosion, Cu line recess, corrosion of submicrometer Cu lines, liner removal selectivity, and contamination of the patterned structures are presented. It was found that minimizing the etch rate (ϳ10 nm/min) of the slurry is required to achieve reproducible removal rates and unrecessed (etched) damascene structures. No dishing was observed with the utilized pad. We also show that corrosion is prone to occur in low Cu pattern density areas and that the removal of the liner material (tantalum) remains problematic because of its chemical inertness.
We describe chemical mechanical polishing (CMP) of blanket and patterned aluminum films employing a polyurethane pad and a slurry based on alumina particles as the abrasive and hydrogen peroxide as the oxidizer. The experiments were conducted at pressures from 19 to 47 kPa and at linear velocities from 26 to 48 m/min, and yielded Al removal rates from 80 to 250 nm/min. The oxidant concentration has a weak effect on the removal rate of Al. Polishing selectivities of Al to silicon dioxide as high as 130:1 were obtained with the maximum selectivities being observed at regions of low pressures and low velocities. The Preston equation fails to describe the dependence of the removal rate on pressure and velocity, and a power function is proposed instead. X-ray photoelectron spectroscopy was used to examine the surface of Al before and immediately after CMP. These experiments provided information on the thickness of the oxidized Al layer. We found that larger removal rates correlated with a smaller Al-oxide thickness.
20 patients with stroke more than one year earlier were evaluated, admitted to a novel therapy including constraint-induced and computer game-motivated therapy. Statistically significant improvements after 4 weeks of late therapy were seen in all 20 patients on nine out of eleven quantified clinical evaluation scales. The patients looked forward to and enjoyed the therapy. These same late stroke patients were studied via fMRI BOLD immediately before therapy and post therapy. fMRI BOLD studies confirm brain functional reorganization; 3 of the 20 fMRI cases are presented here. We propose that fMRI can help in the process of designing effective stroke therapy programs based on biological principles of brain plasticity.
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