c6te atlantique fran~aise pouvant prisenter un inter& medical, nous avons fait un 152 samples (91 species) of marine al-screening antibacterien et antifongique. gae of French Atlantic coast have been Contrairement ? i la presque totaliti des investigated for their antimicrobial (anti-etudes anterieures, ce screening a combacterial and antifungal) activity. For porte un seuil d e detection, nous perrneteach sample, three extracts, prepared tant de mettre en evidence les especes les with E t 2 0 , then E t O H 99 %, then H,O, plus interessantes. were tested. The largest proportion of active species occurs in Cystoseiraceae, Bonnemaisoniaceae and Rhodomelaceae. Partie experimentale lntroduction La mer semble possider un certain pouvoir d ' a~t o e~u r a t i o n bactiriologique. Celui-ci serait dG, en particulier, aux algues [20]. Depuis une vingtaine d'annees, de nombreuses itudes ont ete faites sur ce sujet [2, 7, 14, 16, . .
89 samples (82 species) of marine algae of French Atlantic coast have been investigated in vitro for their potential.antimitotic properties, by vegetable tissue culture technique (inhibition of Helianthus tuberosus growth). For each sample, three extracts, prepared with E t 2 0 , then EtOH 99 %, then H 2 0 , have been tested. Some of the most interesting extracts have also been examinated in vitro by "Helianthus tuberosus test-disc", by crown-gall tissue culture technique, and for their cytotoxicity on KB-cells and for their antimetabolite properties. Results are discussed.
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