In view of the potent antimicrobial and antiinfl ammatory activities exhibited by quinazolin-4-(3H)-ones, a series of novel 2, 3-disubstituted-3,1-quinazolin-4-(3H) ones have been synthesized. The synthesized compounds were screened for antibacterial and antiinfl ammatory activities. Compounds 3a and 3l showed signifi cant antiinfl ammatory activity comparable to ibuprofen, while the compound 3J showed antibacterial activity comparable to ciprofl oxacin.
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