The serial propagation of influenza B (Lee) virus has been demonstrated in a transmissible line of canine kidney cells, as evidenced by the presence of cytopathic effects and hemagglutinins in each of six consecutive tissue-culture passages, and by egg infectivity titers of 10-4.3 and 10-4.1 per 0.1 ml in 3rd and 5th tissue culture fluids, respectively.

INAPPROPRIATE secretion of antidiureticReport of a Case Shormone has been implicated as the cause of the A 32-year-old Taiwanese man, a virology, techniia hyponatremia and renal salt-wasting associated at the US Naval Medical Research Unit No. 2 with certain cases of intracranial and intra-(NAMRU-2), was admitted to Taiwan University Hosthoracic disease. Cases of traumatic, infectious, pital on Sept 16, 1961, with the chief complaint of walking disturbance and pain in the left leg. About four days and neoplastic intracranial disease, and of neoprior to admission he began to have headache, pain plastic thoracic disease have been associated and numbness in the left thigh, and low backache. I • with the salt-wasting syndrome. 14 The follow-These symptoms progressed, the left leg became : .ing is a report of the simultaneous occurrence weak, and he had difficulty walking by the time of in a patient of an illness clinically indistinguish-admission. The patiet had no symptoms of upper-'able from the Guillain-Barr syndrome and of respiratory-tract infection or history of other ante-[u! ,,• " ,•cedent illness. Rapidly ascending paralysis occurred 14 •, an electrolyte disturbance marked by transient during the next few days, and seven days after loss of renal sodium-conserving ability, plasma admission, he had complete quadriplegia and required hypo-osmolality, and plasma hyponatremia. respirator treatment. He was transferred to Immunologic features of this patient's illness NAMRU-2 on Sept 23. The patient had worked with group-B arboviruses suggested to us that the etiology of the poly-from October 1960 to September 1961, the time of radiculoneuropathy was hypersensitivity to onset of illness. This work entailed pipetting virus viral antigens. suspensions, injecting animals, grinding up infected animal brains, and infecting monkeys by the intra-

No abstract