Aim: identification of risk factors of hemorrhagic transformation (HT) after intravenous thrombolytic therapy. Patients and methods: the study included 100 medical records of patients, who underwent thrombolytic therapy. Patients were divided into two groups according to the outcome: 89 patients with HT and 11 patients without HT. Clinical and demographic characteristics of patients were analyzed, including neurological status assessment using NIHSS, Rankin, Rivermead and Waterloo scales. Results: among patients with HT 54.5% were smokers, compared to 29.2% in no HT group (p < 0.05). Significant differences in Rankin, Rivermead and Waterloo scales on admission, after the intervention and at discharge were observed (p < 0.05). Conclusion: smoking is as a significant risk factor of HT, which should be taken into account in the development of thrombolytic therapy programs.
AIM. To evaluate the system of remote rehabilitation for patients after coronavirus infection (COVID-19) in Tyumen region and its first results. MATERIAL AND METHODS. A randomized trial, including 100 cases in patients who had had a moderately severe coronavirus infection. The following were analyzed: dyspnea progression (according to mMRS), the Borg test progression, Stange and Henci functional tests, and quality of life results according to the EQ-5D questionnaire. Telemedicine interaction was carried out using the Telemed72 application. The rehabilitation program included physical exercises and video classes. RESULTS AND DISCUSSION. There were no major problems with remote communication between the patient and the therapist in the course of the telerehabilitation. At the end of the rehabilitation period, two groups showed some positive changes. Group 1 reduced the severity of dyspnea by 2 points, Group 2 – by 1.5 points, the data of functional breathing tests improved, muscle strength increased and self-evaluation of the quality of life also improved. Contact with a medical professional during telerehabilitation sessions and exercising under the remote supervision of a specialist are of great importance for the patient. This preserves the principle of continuity and consistency in rehabilitation care. CONCLUSION. A system of telerehabilitation has been launched in Tyumen region. The patients, participating in remote tele-rehabilitation sessions, demonstrate improvements in functional breathing tests and quality of life scores. Expanding the boundaries of distant rehabilitation beyond large scientific and clinical centres will require training in the use of videoconferencing and operating special equipment.
Уровень качества жизни должен учитываться при оценке эффективности проводимой терапии и качества оказания медицинской помощи.
The aim of the study was to analyze the incidence of arterial hypertension among comorbidities in patients with coronavirus infection, to consider the effect of coronavirus infection on the course of cardiovascular diseases according to instrumental diagnostic methods. Materials and methods: theoretical (analysis and synthesis of studies on the problem); empirical (observation, interviews); methods of quantitative data processing. Results of the study. Based on the analysis of the literature, our own observation and management of patients with arterial hypertension who had new coronavirus infection (COVID 19), we can suggest that therapy with angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers should be continued and their withdrawal during the pandemic is not justified, since at present there are no compelling data to discontinue therapy with renin-angiotensin-aldosterone system blockers to prevent infection or Conclusion. To date, there is no proven theory about the role of the renin-angiotensin-aldosterone system and its blockers in the development of complications and outcomes of coronavirus infection, and drugs from the groups of angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers. Are still vital drugs that determine the prognosis for patients with arterial hypertension, chronic heart failure, coronary heart disease, for those with diabetes, and discontinuation of treatment can have extremely adverse effects, including increased mortality. And the group of patients with concomitant cardiovascular diseases, long-term recipients of drugs from the group of angiotensin-converting enzyme inhibitors or angiotensin II receptor blockers, should be considered, “as a risk group requiring more careful monitoring of the condition” with confirmed SARS-CoV-2 infection.
Aim. To evaluate the severity of encephalopathy and the efficacy of the second stage of rehabilitation in patients with post-infectious encephalopathy. Material and methods. The study included 92 patients with post-infectious encephalopathy, who underwent the second stage of rehabilitation after СOVID-19 infection. All patients were divided into 2 groups: those, who were referred to rehabilitation after the end of the treatment (n=54) and those, who refused to undergo rehabilitation (n=38). In all cases the severity of coronavirus infection, percentage of pulmonary involvement (based on chest CT-findings) and the presence of comorbid pathology were assessed. The severity of the prevailing syndromes was assessed using the International Classification of Functioning, Disability and Health (ICF). Patient status dynamics was assessed using Rehabilitation routing scale (RRS), Rivermead, Holden and Hauser scales. Results and discussion. Post-infectious encephalopathy was mainly accompanied by vestibular ataxia syndrome in 51 (55.4%) patients (in 51.9% and 60.5% patients in groups 1 and 2, respectively) and cerebro-asthenic syndrome in 73 (79.3%) patients (in 72.2% and 89.5% patients in groups 1 and 2, respectively). Comprehensive rehabilitation process is characterized by staging aimed at compensating for all components of pathogenesis that affected during the period of severe course of COVID-19 infection. Rehabilitation was an effective measure for the compensation of neurologic complications of COVID-19 infection. After 2 weeks, cerebro-asthenic syndrome was observed in 24.1% patients in group 1 and 71.0% in group 2 (p <0.05), vestibular ataxia syndrome – in 18.5% and 28.9% (p<0.05) of patients in groups 1 and 2, respectively. The current pandemic is highly likely to be accompanied by a significant increase in the prevalence of encephalopathy affecting the ability to return to daily functioning. Conclusion. The main manifestations of post-covid encephalopathy are cerebro-asthenic (79.3%) and vestibular ataxia (55.4%) syndromes. Therapeutic and rehabilitation measures carried out at the 2nd stage of rehabilitation is an effective measure to compensate for the severity of post-covid encephalopathy.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.